[Clinical analysis of 19 patients with malignant melanoma of the nasal cavity].

Hunan Yi Ke Da Xue Xue Bao

Department of Radiation Oncology, Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha 410008, China.

Published: April 2003

Objective: To explore the pathology, clinical characteristics and treatment of patients with malignant melanoma of the nasal cavity.

Methods: From September, 1988 to July, 2001, 19 patients with malignant melanoma of the nasal cavity were treated in our hospital. All the patients were confirmed by histopathology. The most common symptoms were nasal obstruction and epistaxis. All the patients were treated with surgery(S), 6 with S plus radiotherapy (R), 2 with S plus R plus chemotherapy (C), 3 with S plus C.

Results: Seven cases survived for 8 months to 13 years. The survival rates of 1, 3, 5 years were 64.7%, 42.85%, 30.76% respectively.

Conclusion: Malignant melanoma of the nasal cavity has an aggressive behavior and is easy to recur. S + R is an effective method.

Download full-text PDF

Source

Publication Analysis

Top Keywords

malignant melanoma
16
melanoma nasal
16
patients malignant
12
nasal cavity
8
patients
5
nasal
5
[clinical analysis
4
analysis patients
4
malignant
4
melanoma
4

Similar Publications

Metastatic uveal melanoma (UM) patients often initially present with limited symptoms despite a poor prognosis, complicating communication with patients and caregivers. Early Together (NCT04728113) is a randomized Phase III trial that integrates early palliative care through systematic joint visits involving the palliative care team and the medical oncologist, compared with standard oncological care, in 162 metastatic UM patients beginning systemic treatment. This collaboration aims to enhance patient functioning, improve quality of life and facilitate coping mechanisms.

View Article and Find Full Text PDF

This study summarized the existing evidence on the outcomes and safety of anti-PD-1s, anti-PD-L1s and anti-CTLA-4s in pediatric patients with melanoma. MEDLINE and Embase were searched from database inception to 01-12-2023. Of 1537 records identified, 27 studies (k) of 64 patients were included.

View Article and Find Full Text PDF

Subungual melanoma accounts for 1.9% of cutaneous melanomas. Amelanotic cases, comprising 15-25%, poses a significant diagnostic challenge because it can be misdiagnosed as other traumatic, inflammatory, or neoplastic conditions.

View Article and Find Full Text PDF

This study determined the characteristics of patients with early-stage melanoma (IA-IIA) who later had stage IV recurrence. We retrospectively examined 880 melanoma patients and identified those who progressed to stage IV disease from an initial early-stage (n = 50). We observed a median latent period of 4 years between early-stage diagnosis and metastatic disease.

View Article and Find Full Text PDF

BRAF-mutant melanoma management: a single center retrospective analysis of patients treated with sequential therapy.

Melanoma Manag

December 2024

Department of Medical-Surgical Sciences and Biotechnologies, Dermatology Unit "Daniele Innocenzi", Sapienza University of Rome, Latina, Italy.

Aims: In treating patients with melanoma, the order in which therapy is administered, choosing between targeted therapy and immune checkpoint inhibition, has garnered growing interest.

Patients And Methods: We conducted a retrospective, real-world analysis of patients with advanced melanoma undergoing immunotherapy or targeted therapy as first-line at a single center.

Results: A total of 88 patients diagnosed with melanoma were identified.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!