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Scurvy in an 18-month-old child mimicking a clinical presentation of rickets.
Arch Pediatr
December 2024
General Pediatric Department, Versailles hospital, Le Chesnay, France.
Scurvy is now considered to be a rare disease in European countries, even among children, but it still exists. We report the case of an 18-month-old boy who was initially hospitalized for a walking disorder and ultimately diagnosed with scurvy. Radiographs were compatible with rickets, but biological analysis ruled out this diagnosis.
View Article and Find Full Text PDF[Position statement on the use of amlodipine during pregnancy. Working Group on Hypertension in Women, Argentine Society of Hypertension].
Hipertens Riesgo Vasc
December 2024
Sociedad Argentina de Hipertensión Arterial, Argentina; Hospital Español de Mendoza, Ciudad de Mendoza, Mendoza, Argentina.
Pharmacological management of HDP includes agents supported by extensive evidence ensuring their safety for use. Among those traditionally described in the literature are: alpha-methyldopa, labetalol, and sustained-release nifedipine (NIF-RETARD). These drugs, in addition to being compatible with pregnancy, present additional eligibility criteria.
View Article and Find Full Text PDFPopulation pharmacokinetic modelling of cetirizine concentrations in human breast milk-A contribution from the ConcePTION project.
Basic Clin Pharmacol Toxicol
January 2025
Department of Pharmacy, Pharmacoepidemiology and Drug Safety Research Group, University of Oslo, Oslo, Norway.
Article Synopsis
- Cetirizine is an antihistamine used for treating allergies and is often prescribed to breastfeeding mothers, although its effects on infants through breast milk are not well-documented.
- A population pharmacokinetic (popPK) model was created using data from a study of 35 breastfeeding women to predict cetirizine levels in breast milk and calculate the relative infant dose (RID).
- The study found a mean RID of 1.99%, indicating low exposure for infants, and suggests that cetirizine is generally safe for use during breastfeeding.
Investigating the impact of stochasticity on HIV infection dynamics in CD4 T cells using a reaction-diffusion model.
Sci Rep
October 2024
Department of Electronic and Electrical Engineering, University of Sheffield, Sheffield, South Yorkshire, England.
The disease dynamics affect the human life. When one person is affected with a disease and if it is not treated well, it can weaken the immune system of the body. Human Immunodeficiency Virus (HIV) is a virus that attacks the immune system, of the body which is the defense line against diseases.
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