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Scrub typhus associated with reactive arthritis: A case report and literature review.
IDCases
December 2024
Department of General Internal Medicine, Uonuma Kikan Hospital, Minamiuonuma, Niigata 949-7302, Japan.
Scrub typhus (tsutsugamushi disease) is an acute febrile illness caused by , often found in Asia and Oceania. The presence of an eschar, characterized by a crust, is a key diagnostic finding. Many symptoms of this disease are already known, however reactive arthritis following scrub typhus is very rare.
View Article and Find Full Text PDFA CRISPR-Cas12a-based universal rapid scrub typhus diagnostic method targeting 16S rRNA of Orientia tsutsugamushi.
PLoS Negl Trop Dis
January 2025
Department of Life Science, Gachon University, Seongnam-Si, Republic of Korea.
Scrub typhus is caused by Orientia tsutsugamushi infection and occurs frequently in an area called the Tsutsugamushi Triangle. Currently, there is no vaccine for O. tsutsugamushi, and its infection is treated with antibiotics such as doxycycline.
View Article and Find Full Text PDFScrub typhus in pregnancy: A 10-year multicenter study in resource-limited settings in China.
PLoS Negl Trop Dis
January 2025
Department of Neonatology, National Children's Medical Center/Children's Hospital of Fudan University, National Health Commission (NHC) Key Laboratory of Neonatal Diseases, Shanghai, China.
Background: Despite its association with high mortality rates and negative fetal outcomes, large-scale epidemiological studies on scrub typhus (ST) during pregnancy remain scarce.
Methods: We conducted a retrospective, multicenter study by collecting 260 pregnant women with ST in China across a 10-year time period to evaluate how clinical characteristics changed over this time and identify risk factors for poor fetal outcome.
Results: In total, 78.
Molecular Assay Versus Serology for Diagnosis of Scrub Typhus Among Patients With Acute Febrile Illness: A Retrospective Study.
Cureus
December 2024
Microbiology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Background And Objectives: The epidemiology of scrub typhus caused by has been growing in Odisha, India. The most common symptoms include fever, cough, lymphadenopathy, eschar, and rash. In India, enzyme-linked immunosorbent assays (ELISA) and DNA real-time polymerase chain reaction (DNA RT-PCR) are the most commonly used methods to diagnose scrub typhus.
View Article and Find Full Text PDFThe diagnostic accuracy of point-of-care nucleic acid-based isothermal amplification assays for scrub typhus: a systematic review and meta-analysis.
Front Microbiol
January 2025
Department of Epidemiology & Public Health, Central University of Tamil Nadu, Thiruvarur, India.
Introduction: The diagnosis and detection of pathogens such as and is a cause of major concern among the public health community. Unavailability of rapid, cost-effective diagnostic assays contributes to delayed diagnosis and timely treatment. Using the methodology of systematic reviewing and meta-analysis, the study aimed to synthesize and compare the diagnostic performances of all the available isothermal assays for the detection of classical rickettsial diseases.
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