Pretreatment with mexidol (100 mg/kg) offered protection under the conditions of acute (3 h) liver damage in rats under the conditions of immobilization stress. The drug inhibited lipid peroxidation, enhanced intrinsic antioxidant protection function, and normalized the activity of enzymes-markers of hepatocyte damage. In addition, the treatment with mexidol normalized the level of bilirubin in the blood serum and stimulated the detoxicating function of liver in the bromsulphalein test.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
[pharmacological activity
4
activity mexidol
4
mexidol stress-induced
4
stress-induced liver
4
liver damage]
4
damage] pretreatment
4
pretreatment mexidol
4
mexidol 100
4
100 mg/kg
4
mg/kg offered
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!