Memory functions and focussed attention in middle-aged and elderly subjects are unaffected by a low, acute dose of caffeine.

J Nutr Health Aging

Experimental Psychopharmacology Unit, Brain and Behaviour Institute, Universiteit Maastricht, Maastricht, The Netherlands.

Published: December 2003

The putative beneficial effects of caffeine on cognitive performance may vary between ages. The acute cognitive effects of 100 g caffeine on memory functions and focussed attention were investigated in sixteen middle-aged (45-60 years) and fourteen elderly (60-75 years) healthy men and women according to a cross-over design. Caffeine did not affect short-term memory span or speed, long-term memory retrieval functions or focussed attention. It is proposed that in middle-aged and elderly subjects cognitive effects may occur predominantly at higher caffeine dosages.

Download full-text PDF

Source

Publication Analysis

Top Keywords

functions focussed
12
focussed attention
12
memory functions
8
middle-aged elderly
8
elderly subjects
8
cognitive effects
8
caffeine
5
memory
4
attention middle-aged
4
subjects unaffected
4

Similar Publications

Introduction: Haemodynamic atrioventricular delay (AVD) optimisation has primarily focussed on signals that are not easy to acquire from a pacing system itself, such as invasive left ventricular catheterisation or arterial blood pressure (ABP). In this study, standard clinical central venous pressure (CVP) signals are tested as a potential alternative.

Methods: Sixteen patients with a temporary pacemaker after cardiac surgery were studied.

View Article and Find Full Text PDF

Introduction: Fibromyalgia has a high female predominance and research work has been focussing mainly on women.

Objectives: We aimed to answer (1) gender differences in pain scores and quality of life, (2) any gender-specific subgroups defined by quantitative sensory testing (QST), and (3) correlations of QST parameters with pain intensity and questionnaire scores.

Methods: We evaluated clinical presentations and QST profiles from 38 male and 38 age-matched female patients.

View Article and Find Full Text PDF

'It Feels Very Weird and Normal at the Same Time': Sibling Perceptions of Their Relationships With an Autistic Brother or Sister With Complex Care Needs.

J Appl Res Intellect Disabil

January 2025

The Autism Community Research Network @Southampton [ACoRNS] and the Centre for Research in Mental Health, School of Psychology, University of Southampton, Southampton, UK.

Background: The impact of having a disabled brother or sister on siblings' psychological well-being and sibling relationships has been the subject of several research studies. However, research which focuses on the relationship between siblings and their autistic brother or sister with an intellectual disability and complex care needs is rare. We explored siblings' views and experiences of their sibling relationship with their autistic brother or sister with complex care needs.

View Article and Find Full Text PDF

Preparation of ethynylsulfonamides and study of their reactivity with nucleophilic amino acids.

Org Biomol Chem

January 2025

Laboratory of Drug Design and Medicinal Chemistry, Showa Pharmaceutical University, 3-2-1 Higashi-Tamagawagakuen, Machida, Tokyo 194-8543, Japan.

The development of covalent drugs, particularly those utilizing Michael acceptors, has garnered significant attention in recent pharmaceutical research due to the ability of such molecules to irreversibly inhibit protein function. This study focusses on the synthesis and evaluation of ethynylsulfonamides, which are predicted to have superior covalent binding ability, metabolic stability, and water solubility compared to traditional amides. We developed a straightforward synthesis method for ethynylsulfonamides and comprehensively evaluated the covalent binding abilities of these compounds using NMR with various nucleophilic amino acids in different solvents.

View Article and Find Full Text PDF

Prehabilitation has become a field of increasing interest over recent decades. However, few studies specifically investigated prehabilitation for older patients with cancer. The objective of this umbrella review was to summarize evidence on prehabilitation programs to identify the physical interventions that may be applied with benefit to older cancer patients who will undergo complex medical-surgical procedures.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!