Holographic interferometry measurements have been performed on high-speed, high-temperature gas flows with a laser output tuned near a resonant sodium transition. The technique allows the detection and quantification of the sodium concentration in the flow. By controlling the laser detuning and seeded sodium concentration, we performed flow visualization in low-density flows that are not normally detectable with standard interferometry. The technique was also successfully used to estimate the temperature in the boundary layer of the flow over a flat plate.
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http://dx.doi.org/10.1364/ao.42.004445 | DOI Listing |
Eur J Nucl Med Mol Imaging
January 2025
Departments of Radiology and Medical Physics, University of Wisconsin - Madison, Madison, WI, 53705, USA.
Purpose: Trophoblast cell-surface antigen 2 (Trop2) is overexpressed in various solid tumors and contributes to tumor progression, while its expression remains low in normal tissues. Trop2-targeting antibody-drug conjugate (ADC), sacituzumab govitecan-hziy (Trodelvy), has shown efficacy in targeting this antigen. Leveraging the enhanced specificity of ADCs, we conducted the first immunoPET imaging study of Trop2 expression in gastric cancer (GC) and triple-negative breast cancer (TNBC) models using Zr-labeled Trodelvy ([Zr]Zr-DFO-Trodelvy).
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
January 2025
Institute of Radiation Medicine, Fudan University, Xietu Road 2094, Shanghai, 200032, China.
Objectives: Mesothelin (MSLN) is an antigen that is overexpressed in various cancers, and its interaction with tumor-associated cancer antigen 125 plays a multifaceted role in tumor metastasis. The serum MSLN expression level can be detected using enzyme-linked immunosorbent assay; however, non-invasive visualization of its expression at the tumor site is currently lacking. Therefore, the aim of this study was to develop a molecular probe for imaging MSLN expression through positron emission tomography (PET).
View Article and Find Full Text PDFFront Bioeng Biotechnol
January 2025
School of Athletic Performance, Shanghai University of Sport, Shanghai, China.
Objectives: To explore the acute intervention effects of tissue flossing on chronic knee pain (CKP) in boxers.
Methods: Eighteen boxers with CKP (12 male/6 female) were randomly divided into an experimental group (EG) with tissue flossing (n = 9) and a control group (CG) (n = 9). The visual analog scale (VAS), Lysholm knee function score, flexion range of motion (ROM), maximal isometric extensor muscle strength, and stability of the knee were measured pre- and post-intervention (EG: 3-minute tissue flossing, CG: rest).
Belitung Nurs J
January 2025
Doctorate Program of Medical and Health Science, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Background: Acupressure is a popular form of complementary nursing among adults. It stimulates the body's self-healing processes by enhancing energy flow, or "chi," along meridian channels. Acupressure can address many health issues and is also used on children because it is painless and straightforward.
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
Mathematics and Computer Science Department, University of the Balearic Islands, Ctra Valldemossa, Km 7.5, Palma, 07122, Balearic Islands, Spain.
Background: MetaDAG is a web-based tool developed to address challenges posed by big data from omics technologies, particularly in metabolic network reconstruction and analysis. The tool is capable of constructing metabolic networks for specific organisms, sets of organisms, reactions, enzymes, or KEGG Orthology (KO) identifiers. By retrieving data from the KEGG database, MetaDAG helps users visualize and analyze complex metabolic interactions efficiently.
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