AI Article Synopsis
- The study investigated how various risk factors like high blood sugar, high blood pressure, high cholesterol, and high uric acid affect damage to blood vessels in diabetic patients.
- It involved 61 patients, primarily with type 2 diabetes, measuring endothelial damage using von Willebrand factor levels.
- The findings revealed that while controlling diabetes alone didn’t significantly reduce endothelial damage, managing hypertension along with diabetes did lead to notable improvements in blood vessel health.
Article Abstract
In this study, the effect of different risk factors (hyperglycemia, hypertension, hyperlipidemia, hyperuricemia) on endothelial damage was evaluated in 61 (two of them were type 1; the other patients were type 2) diabetic patients. von Willebrand factor antigen was used as the marker of the endothelial damage. Although there was no significant decrease (P > 0.05) in von Willebrand factor level after regulation of nonregulated diabetes, a significant decrease was determined in nonregulated and hypertensive diabetic patients after improvement of risk factors (P < 0.05). As a result, nonregulated diabetes alone has less effect than nonregulated diabetes plus other risk factors (particularly hypertension) on diabetic angiopathy.
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| http://dx.doi.org/10.1097/01.SMJ.0000054908.81096.4F | DOI Listing |
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