AI Article Synopsis
- The paper focuses on improving the spatiotemporal resolution in MRI scans of rat kidneys using ultra-small superparamagnetic iron oxide (USPIO) contrast agents.
- It introduces a generalized series-based imaging technique that minimizes the coverage needed in kappa-space, effectively reducing the number of phase encodings by four times without significantly degrading image quality.
- This advancement aims to facilitate 3D imaging studies and enhance early detection of kidney rejection following transplantation.
Article Abstract
This paper addresses the problem of enhancing spatiotemporal resolution of ultra-small superparamagnetic iron oxide (USPIO)-enhanced dynamic MRI of rat kidneys. To alleviate the limited resolution problem of conventional full-scan Fourier imaging methods, we use a generalized series-based imaging scheme to reduce coverage of kappa-space. Experimental results demonstrate that the generalized series imaging method with basis functions constructed using two references (pre- and post-contrast) can reduce the number of phase encodings measured during the dynamic contrast wash-in process by a factor of 4 with a negligible or minimal loss of image quality. The method is expected to make 3D studies possible using USPIO-enhanced dynamic imaging of rat kidneys, and prove valuable for early detection of renal rejection after kidney transplantation.
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| http://dx.doi.org/10.1016/s0730-725x(03)00089-4 | DOI Listing |
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