Aim: To look for new active constituents from Chinese medicine "Sheng-ma", rhizome of Cimicifuga foetida L.
Methods: The compounds were separated and purified by chromatography on silica gel and Sephadex LH-20. Their structures were determined by spectral analysis and chemical reaction.
Results: Eight compounds were obtained and identified as cimicifugic acid (1), esculetin (2), caffeic acid methyl ester (3), 4-O-acetyl-caffeic acid (4), sinapic acid (5), caffeic acid (6), ferulic acid (7), isoferulic acid (8).
Conclusion: Compound 1 is a new compound, and compounds 2-7 were isolated from this plant for the first time.
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