In computed tomography (CT), selection of a convolution kernel determines the tradeoff between image sharpness and pixel noise. For certain clinical applications it is desirable to have two or more sets of images with different settings. So far, this typically requires reconstruction of several sets of images. We present an alternative approach using default reconstruction of sharp images and online filtering in the spatial domain allowing modification of the sharpness-noise tradeoff in real time. A suitable smoothing filter function in the frequency domain is the ratio of smooth and original (sharp) kernel. Efficient implementation can be achieved by a Fourier transform of this ratio to the spatial domain. Separating the two-dimensional spatial filtering into two subsequent one-dimensional filtering stages in the x and y directions using a Gaussian approximation for the convolution kernel further reduces computational complexity. Due to efficient implementation, interactive modification of the filter settings becomes possible, which can completely replace the variety of different reconstruction kernels.
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http://dx.doi.org/10.1109/TMI.2003.815073 | DOI Listing |
Case Rep Genet
January 2025
Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California, 2825 50th Street, Davis, Sacramento 95817, California, USA.
Fragile X syndrome (FXS) presents with autism spectrum disorder (ASD), intellectual disability, developmental delay, seizures, hypotonia during infancy, joint laxity, behavioral issues, and characteristic facial features. The predominant mechanism is due to CGG trinucleotide repeat expansion of more than 200 repeats in the 5'UTR (untranslated region) of (Fragile X Messenger Ribonucleoprotein 1) causing promoter methylation and transcriptional silencing. However, not all patients presenting with the characteristic phenotype and point/frameshift mutations with deletions in have been described in the literature.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
Henan Key Laboratory of Imaging and Intelligent Processing, Information Engineering University, Zhengzhou, China.
Background: Photon-counting computed tomography (CT) is an advanced imaging technique that enables multi-energy imaging from a single scan. However, the limited photon count assigned to narrow energy bins leads to increased quantum noise in the reconstructed spectral images. To address this issue, leveraging the prior information in the spectral images is essential.
View Article and Find Full Text PDFMed Phys
January 2025
Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.
Background: Dedicated breast computed tomography (bCT) systems offer detailed imaging for breast cancer diagnosis and treatment. As new bCT generations are developed, it is important to evaluate their imaging performance and dose efficiency to understand differences over previous models.
Purpose: To characterize the imaging performance and dose efficiency of a second-generation (GEN2) bCT system and compare them to those of a first-generation (GEN1) system.
Magn Reson Med
January 2025
Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.
Purpose: To develop and evaluate a physics-driven, saturation contrast-aware, deep-learning-based framework for motion artifact correction in CEST MRI.
Methods: A neural network was designed to correct motion artifacts directly from a Z-spectrum frequency (Ω) domain rather than an image spatial domain. Motion artifacts were simulated by modeling 3D rigid-body motion and readout-related motion during k-space sampling.
BMC Res Notes
January 2025
Department of Mathematics, Jimma University, Jimma, Ethiopia.
Objective: In this work, singularly perturbed time dependent delay parabolic convection-diffusion problem with Dirichlet boundary conditions is considered. The solution of this problem exhibits boundary layer at the right of special domain. In this layer the solution experiences steep gradients or oscillation so that traditional numerical methods may fail to provide smooth solutions.
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