The present study was based on the finding of a case of prepubertal periodontitis, a low prevalence pathology. One hundred and fifty-two infant patients attending the Department of Odontopediatrics of the Faculty of Dentistry of the National University of Rosario over the period April 1995-September 1996 were included in the present study. The reason for consultation was dental caries. However, the high general prevalence of gingivitis (50%) was remarkable. This may be due to deficient oral health care awareness at home and at school. The prevalence of prepubertal periodontitis (PPP) in the population under study (one case of localized PPP) was 0.66%. These data are in agreement with international reports that account for a prevalence value of less than 1%. A relevant difference with other reported cases could be that this patient complained of upper respiratory tract disorders and, occasionally, ear infections. These symptoms appear in the generalized but not the localized forms of the disease.
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PLoS Pathog
January 2025
School of Clinical Dentistry, University of Sheffield, Sheffield, United Kingdom.
Porphyromonas gingivalis (Pg) is a keystone pathogen in periodontitis, a highly prevalent disease manifested by chronic inflammation of the periodontium, alveolar bone resorption and tooth loss. During periodontitis pathobionts such as Pg can enter the bloodstream and growing evidence correlates periodontitis with increased risk of cardiovascular and neurodegenerative diseases. However, the mechanism by which immune cells respond to Pg challenge in vivo remains elusive.
View Article and Find Full Text PDFThe Aim Of The Study: To study the expression of NOD receptors of immunotropic periodontal tissue cells in patients with aggressive periodontitis before and after complex treatment.
Materials And Methods: 15 patients aged 22 to 36 years with aggressive periodontitis were examined before and 21 days after the start of complex treatment. 15 patients with fibroids of the oral mucosa without signs of inflammation served as controls.
Iran J Med Sci
November 2024
Department of Oral Biology, Division of Forensic Odontology, Faculty of Dentistry, University of Indonesia, Jakarta 10430, Indonesia.
Aggressive periodontitis is an inflammation of the periodontal tissue that usually affects adolescents and young adults aged <30 years, caused by attachment loss and fast bone degradation. The correlation between the epigenetic status and the initiation and progression of numerous acquired diseases was documented. Consequently, targeting epigenetic factors within periodontal tissues stands as an appealing prospect for both the diagnosis and treatment of periodontitis.
View Article and Find Full Text PDFCureus
October 2024
Oral Surgery and Implantology, Dental Square Clinic, Beirut, LBN.
Periodontitis is a biofilm-induced chronic inflammatory disease that, if left untreated, can result in alveolar bone and tooth loss. Intrabony defects and furcation involvement (FI) are particularly difficult to manage, as they often persist after step 1 and step 2 periodontal therapy. In this case, we report a relatively novel therapeutic approach to managing deep furcation involvement in the first mandibular right molar (#46).
View Article and Find Full Text PDFClin Oral Investig
November 2024
Department of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.
Objectives: LTF SNP rs1126478 (T>C) could modulate Lactoferrin function and release and has been associated with periodontal disease in different locations before, but not in America. Thus, this study aimed to assess the association between this SNP and Grade C Periodontitis (Generalized (PerioC-G) and Molar Incisor Pattern (PerioC-MIP)) and seek a relationship between its presence and LTF gingival crevicular fluid (GCF) production.
Material And Methods: Oral cells from 361 Brazilians and 375 North Americans patients (Diseased and Health Controls (PH) from both locations) were collected.
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