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Pregnancy: a cloned horse born to its dam twin. | LitMetric

Pregnancy: a cloned horse born to its dam twin.

Nature

Laboratorio di Tecnologie della Riproduzione, CIZ srl, Istituto Sperimentale Italiano Lazzaro Spallanzani, 26100 Cremona, Italy.

Published: August 2003

AI Article Synopsis

Article Abstract

Several animal species, including sheep, mice, cattle, goats, rabbits, cats, pigs and, more recently, mules have been reproduced by somatic cell cloning, with the offspring being a genetic copy of the animal donor of the nuclear material used for transfer into an enucleated oocyte. Here we use this technology to clone an adult horse and show that it is possible to establish a viable, full-term pregnancy in which the surrogate mother is also the nuclear donor. The cloned offspring is therefore genetically identical to the mare who carried it, challenging the idea that maternal immunological recognition of fetal antigens influences the well-being of the fetus and the outcome of the pregnancy.

Download full-text PDF

Source
http://dx.doi.org/10.1038/424635aDOI Listing

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