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Probiotics in piglet: from gut health to pathogen defense mechanisms.
Front Immunol
November 2024
National Engineering Laboratory of Biological Feed Safety and Pollution Prevention and Control, Key Laboratory of Animal Nutrition and Feed, Ministry of Agriculture, Key Laboratory of Animal Nutrition and Feed Science of Zhejiang Province, Institute of Feed Science, Zhejiang University, Hangzhou, Zhejiang, China.
Various problems and obstacles are encountered during pig farming, especially the weaning phase when switching from liquid to solid feed. Infection by pathogenic bacteria causes damage to the intestinal barrier function of piglets, disrupts the balance of the intestinal microbiota, and destroys the chemical, mechanical, and immune barriers of the intestinal tract, which is one of the main causes of gut inflammation or gut diseases in piglets. The traditional method is to add antibiotics to piglet diets to prevent bacterial infections.
View Article and Find Full Text PDFIntegrated Microbiome and Metabolomics Analysis of the Effects of Dietary Supplementation with Corn-Steep-Liquor-Derived Feed on Black Pigs.
Animals (Basel)
January 2024
College of Animal Sciences, Jilin University, Changchun 130062, China.
Article Synopsis
- The experiment used glucose master liquor and corn steep liquor to optimize yeast feed for fermentation, achieving an optimal mixture with specific concentrations yielding good yeast growth.
- The yeast feed was given to groups of black piglets, comparing a control group with one receiving the feed, which showed no impact on growth performance or serum biochemical indices.
- However, the piglets receiving the yeast feed demonstrated significant changes in fecal microbiota and certain plasma metabolites, indicating the feed helped regulate gut bacteria and metabolic levels without negatively affecting growth.
Porcine Reproductive and Respiratory Syndrome (PRRS) and Resistance Polymorphic Markers: What Is the Scenario in Naturally Infected Pig Livestock in Central Italy?
Animals (Basel)
July 2023
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche-Togo Rosati (IZSUM), Via Salvemini 1, 06126 Perugia, Italy.
Article Synopsis
- PRRS virus affects pigs globally, leading to significant losses, particularly in piglets and pregnant sows, with outcomes influenced by strain virulence, environmental factors, and genetics.
- A study analyzed genetic variations (polymorphisms) in slaughtered pigs from Central Italy, extracting RNA from 377 samples and detecting viral RNA to classify animals as infected or not.
- The research identified 36 haplotypes and 62 genotypes, with three linked to potential disease resistance, marking a pioneering investigation that contributes valuable insights for improving resistance to PRRS through Marker-Assisted Selection (MAS).
Effects of Feeding 5-Aminolevulinic Acid on Iron Status in Weaned Rats from the Female Rats during Gestation and Lactation.
Animals (Basel)
October 2022
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Daizong Street 61#, Tai'an 271018, China.
Using female Sprague−Dawley (SD) rats as a model, the current study aimed to investigate whether feeding 5-aminolevulinic acid (5-ALA) to female SD rats during gestation and lactation can affect the iron status of weaned rats and provide new ideas for the iron supplementation of piglets. A total of 27 pregnant SD rats were randomly assigned to three treatments in nine replicates, with one rat per litter. Dietary treatments were basal diet (CON), CON + 50 mg/kg 5-ALA (5-ALA50), and CON + 100 mg/kg 5-ALA (5-ALA100).
View Article and Find Full Text PDFClinical outcome and gut development after insulin-like growth factor-1 supplementation to preterm pigs.
Front Pediatr
August 2022
Comparative Pediatrics and Nutrition, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark.
Background: Elevation of circulating insulin-like growth factor-1 (IGF-1) within normal physiological levels may alleviate several morbidities in preterm infants but safety and efficacy remain unclear. We hypothesized that IGF-1 supplementation during the first 1-2 weeks after preterm birth improves clinical outcomes and gut development, using preterm pigs as a model for infants.
Methods: Preterm pigs were given vehicle or recombinant human IGF-1/binding protein-3 (rhIGF-1, 2.
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