We compared the results of Gram staining and culture of cerebrospinal fluid to results obtained with a rapid PCR assay for the diagnosis of meningococcal meningitis in 281 cases of suspected bacterial meningitis. PCR had a sensitivity of 97% compared to a sensitivity of 55% for culture, and the PCR specificity was 99.6%. PCR results were available within 2 h of the start of the assay.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC179789 | PMC |
| http://dx.doi.org/10.1128/JCM.41.8.3851-3853.2003 | DOI Listing |
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