Safety of the newer antihypertensive agents in children.

Expert Opin Drug Saf

Pediatric Nephrology, School of Medicine, University of Missouri-Kansas City, Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA.

Published: May 2002

Hypertension is relatively uncommon in children and few children receive antihypertensive medications. This article reviews the safety of calcium channel blockers, angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists in children with hypertension. While the newer antihypertensive agents appear to be well-tolerated by children, further studies are needed to determine the safety profile across the developmental continuum, with chronic dosing and in children with complex hypertension.

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http://dx.doi.org/10.1517/14740338.1.1.39DOI Listing

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