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Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study.
Medicina (Kaunas)
October 2024
Faculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, Turkey.
Article Synopsis
- The study focuses on tendon injuries in complex wounds of the hand and lower extremities, exploring how different types of adipofascial tissue flaps affect healing and functional recovery.
- It compares vascularised versus nonvascularised adipofascial flaps using Wistar Albino rats, assessing healing through scintigraphic evaluations and histopathological analysis.
- Results indicate that vascularised flaps promote faster healing while pedicle-free flaps also aid tendon recovery without complications, providing insights for improving tendon repair techniques in reconstructive surgery.
Biomarkers of bone metabolism in [Ra] RaCl therapy - association with extent of disease and prediction of overall survival.
EJNMMI Res
October 2024
Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Background: The alpha-emitting radionuclide therapy [Ra]RaCl (Radium-223) improves overall survival (OS) and time to symptomatic skeletal event (SSE) in patients with metastatic castration-resistant prostate cancer (mCRPC). Evidence suggests that the effect of Radium-223 is partly exerted through an impact on the surrounding bone matrix. We hypothesized that bone metabolism markers (BMM) could provide predictive information regarding response to Radium-223.
View Article and Find Full Text PDFDetermination of Critical Organ Doses with Lu Prostate-specific Membrane Antigen Dosimetry in Metastatic Prostate Cancer Treatment.
J Med Phys
June 2024
Department of Nuclear Medicine, Cerrahpaşa Faculty of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Turkey.
Aim: This study aimed to perform dosimetry in patients with metastatic prostate cancer treated with Lutetium (Lu) prostate-specific membrane antigen (PSMA)-617 radiopharmaceutical, calculating organ blood clearance and consequently determining the maximum tolerable treatment activity.
Materials And Methods: Eighteen patients with metastatic prostate cancer were enrolled in the study. Patients were administered 5.
Early Diagnosis of Amyloidosis and Cardiac Involvement through Carpal Tunnel Surgery and Predictive Factors.
J Clin Med
July 2024
Gastroenterology Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT), 08208 Sabadell, Spain.
: To determine the prevalence of amyloidosis through the analysis of synovial tissue and transverse carpal ligament (TCL) in patients undergoing surgery for carpal tunnel syndrome (CTS), detect predictive factors for the presence of amyloid, and assess cardiac involvement degree. : A prospective study with longitudinal cohort follow-up at a teaching hospital. Patients undergoing CTS surgery from 1 January 2019 to 31 May 2021 were included.
View Article and Find Full Text PDFA Severe Case of Spontaneous Intracranial Hypotension in an Adult Asian Male Improved With Trendelenburg Positioning: A Case Report.
Cureus
May 2024
Institute for Neurosciences, St. Luke's Medical Center, Quezon City, PHL.
Non-traumatic bilateral acute subdural hematomas are a rare occurrence. Etiologies typically include, but are not limited to, cortical artery bleeding, vascular lesions, coagulopathies, and spontaneous intracranial hypotension. We report a case of a 45-year-old Korean male with no known co-morbid illnesses nor history of head or neck trauma, who came to the emergency department due to a 10-day history of dizziness and head heaviness, followed by disorientation and drowsiness.
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