Background: Guidelines on cardiopulmonary resuscitation (CPR) recommend that decisions about resuscitation are part of every patient's care plan. We aimed to ascertain the initial views of a haemodialysis cohort in the UK regarding their CPR status in the event of an in-hospital cardiac arrest not related to dialysis.
Methods: During outpatient clinic follow-up between January and March 2001, 66 haemodialysis patients were interviewed by one of two interviewers. A standard interview format was used, which included information on complications and outcome of CPR in haemodialysis patients. Patients had no prior opportunity to discuss the issue with a third party.
Results: Fifty patients (76%) wished to receive CPR. Five patients decided against CPR, of whom two were depressed. Six patients were undecided. Five patients were excluded from the analysis because of lack of mental capacity or language difficulties. Patients who wished to receive CPR were significantly younger (59 +/- 16 vs 74 +/- 10 years, respectively; P < 0.01) and had a significantly higher serum albumin level compared with those who did not opt for CPR or were undecided. There was no difference in gender, comorbidity, length of time on dialysis, proportion of patients with adequate dialysis and mean haemoglobin level between those who wished CPR and those who did not.
Conclusions: The majority of haemodialysis patients wished to receive CPR. These patients were younger than those who did not opt for CPR. Clearer strategies on third-party consultation and follow-up interviews are needed to guarantee that patients' wishes are respected at all times.
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http://dx.doi.org/10.1093/ndt/gfg266 | DOI Listing |
Aging Clin Exp Res
January 2025
The College of Nursing, Zhejiang Chinese Medical University, Hangzhou, China.
Background: Many studies have developed or validated predictive models to estimate the risk of sarcopenia in dialysis patients, but the quality of model development and the applicability of the models remain unclear.
Objective: To systematically review and critically evaluate currently available predictive models for sarcopenia in dialysis patients.
Methods: We systematically searched five databases until March 2024.
Lupus
January 2025
Mansoura Nephrology and Dialysis Unit, Mansoura University, Mansoura, Egypt.
Background: Endoplasmic reticulum stress with protein misfolding has been introduced as a key pathogenetic mechanism in lupus nephritis (LN). Pregnancy is thought to exaggerate proteostasis, which leads to the accumulation of potentially pathogenic misfolded proteins in the urine, serum, and placenta particularly in women with preeclampsia. The detection of misfolded proteins is made using Congo red stain, which is referred to as congophilia.
View Article and Find Full Text PDFTrans R Soc Trop Med Hyg
January 2025
Department of Clinical Medicine, Faculty of Medicine, University of Colombo, P.O. 00800, Sri Lanka.
Snakebite-associated acute kidney injury (AKI) poses a significant health burden in the South Asia region, resulting in considerable morbidity and mortality. Multiple factors contribute to the pathogenesis of AKI following snakebites, including hypotension, intravascular haemolysis, disseminated intravascular coagulation, rhabdomyolysis, thrombotic microangiopathy (TMA) and direct nephrotoxicity. Clinical features manifest as anuria, oliguria, haematuria, abdominal pain and hypertension.
View Article and Find Full Text PDFFront Immunol
January 2025
Department of Nephrology, Second Hospital of Jilin University, Changchun, China.
Long-term exposure of the peritoneum to peritoneal dialysate results in pathophysiological changes in the anatomical organization of the peritoneum and progressive development of peritoneal fibrosis. This leads to a decline in peritoneal function and ultrafiltration failure, ultimately necessitating the discontinuation of peritoneal dialysis, severely limiting the potential for long-term maintenance. Additionally, encapsulating peritoneal sclerosis, a serious consequence of peritoneal fibrosis, resulting in patients discontinuing PD and significant mortality.
View Article and Find Full Text PDFKidney Res Clin Pract
December 2024
Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.
Background: Although the introduction of erythropoietin-stimulating agents (ESAs) has led to better clinical outcomes in patients undergoing hemodialysis (HD), fluctuations in hemoglobin (Hb) levels, known as Hb variability, are frequently observed. However, only a few studies have evaluated the association between Hb variability and nutritional status in patients undergoing HD.
Methods: In this prospective study conducted between March 1, 2020, and June 1, 2022, we included 109 patients aged over 20 years undergoing HD and receiving darbepoetin.
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