How do you obtain a valid assessment of subjective outcomes in a trial in which the participants cannot be blinded to the intervention? Bias is inevitable from unblinded patients, but trials that have not told patients about treatment in all arms have been heavily criticised. Asking participants to consent to postponed information could be a solution
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1126664 | PMC |
| http://dx.doi.org/10.1136/bmj.327.7409.284 | DOI Listing |
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