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Dr. Kiyoshi Shiga (1871-1957): Outstanding Bacteriologist Who Discovered Dysentery Bacillus and Contributed Immensely to Public Health in Japan.
Cureus
October 2024
Urogynecology, Yokosuka Urogynecology and Urology Clinic, Kanagawa, JPN.
Kiyoshi Shiga (1871-1957) was a renowned Japanese bacteriologist best known for discovering the dysentery bacillus. Born in Sendai during the Meiji Restoration, Shiga graduated from Tokyo Imperial University's School (later University of Tokyo) of Medicine and began microbiological research under Shibasaburo Kitasato. In 1897, during a dysentery () epidemic, he isolated and identified the causative organism (later named ) using Koch's postulates, laying the foundation for enteric disease research.
View Article and Find Full Text PDFADOPTERs of Innovation in a Crisis: The History of Vera Gedroits, Kanehiro Takaki and the Russo-Japanese War of 1904-1905.
Ann Surg Open
June 2024
Department of Upper Gastrointestinal Surgery, University of New South Wales, Liverpool Hospital, Liverpool, NSW, Australia.
The 1904-1905 Russo-Japanese War was the first "modern" conflict, using rapid-firing artillery and machine guns, fought over imperial ambitions in Korea and Manchuria. During the war, Princess Vera Gedroits pioneered early laparotomy for penetrating abdominal wounds with unprecedented success. Her techniques were then adopted by the Russian Society of Military Doctors.
View Article and Find Full Text PDFThe role of CT brain findings in the early diagnosis of infantile encephalitic beriberi.
Neuroradiology
June 2024
Department of Pediatrics, Govt Medical College, Srinagar, J&K, India.
Background: Thiamine deficiency disease may occur in infants from thiamine-deficient mothers in developing countries, as well as in infants fed solely with soy-based formula. Thiamine deficiency in infants may present with acute neurological manifestations of infantile encephalitic beriberi.
Objective: To review the role of noncontrast CT brain findings in infantile encephalitic beriberi in early diagnosis.
Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi.
Palliat Support Care
March 2024
Department of Psycho-oncology, Saitama Medical University International Medical Center, Hidaka City, Saitama, Japan.
Article Synopsis
- - An 82-year-old woman with advanced cervical cancer experienced significant anorexia and neurological symptoms, which were linked to thiamine deficiency (TD) during her palliative care treatment.
- - After receiving intravenous thiamine, her symptoms improved dramatically, and her dietary intake significantly increased.
- - This case highlights the importance of recognizing TD as a potential cause of anorexia in cancer patients, suggesting that proper diagnosis and treatment can enhance their quality of life.
A Predictive Model for Thiamine Responsive Disorders Among Infants and Young Children: Results from a Prospective Cohort Study in Lao People's Democratic Republic.
J Pediatr
May 2024
Institute for Global Nutrition and Department of Nutrition, University of California Davis, Davis, CA.
Objective: To develop a predictive model for thiamine responsive disorders (TRDs) among infants and young children hospitalized with signs or symptoms suggestive of thiamine deficiency disorders (TDDs) based on response to therapeutic thiamine in a high-risk setting.
Study Design: Children aged 21 days to <18 months hospitalized with signs or symptoms suggestive of TDD in northern Lao People's Democratic Republic were treated with parenteral thiamine (100 mg daily) for ≥3 days in addition to routine care. Physical examinations and recovery assessments were conducted frequently for 72 hours after thiamine was initiated.
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