AI Article Synopsis
- Schizophrenia patients tend to make more errors on antisaccade tasks compared to nonpsychiatric controls, highlighting a potential cognitive deficit associated with the disorder.
- Studies have shown that while some research suggests relatives of schizophrenia patients also show increased antisaccade errors, this study found no significant differences between first-degree relatives of schizophrenia patients and nonpsychiatric controls.
- The results indicate that elevated antisaccade errors are linked to schizophrenia itself, but not necessarily as a hereditary trait among relatives.
Article Abstract
Numerous studies have replicated the finding that schizophrenia patients make an increased number of errors on an antisaccade task. Some studies have reported that relatives of schizophrenia patients also make an increased number of antisaccade errors, a finding that has been interpreted to support the usefulness of compromised antisaccade performance as an index of genetic liability for schizophrenia. We examined performance on an antisaccade task in schizophrenia patients, nonpsychiatric controls, first-degree relatives of schizophrenia patients and first-degree relatives of nonpsychiatric controls. Schizophrenia patients made significantly more errors than did nonpsychiatric controls, but relatives of schizophrenia patients did not differ from relatives of controls or from all controls. Increased antisaccade errors on the standard version of the antisaccade task are associated with schizophrenia, but do not seem to be a co-familial trait for schizophrenia.
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| http://dx.doi.org/10.1016/s0920-9964(02)00438-3 | DOI Listing |
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