This short paper examines developments in expert evidentiary procedures in forensic cases in Hungary. The basis of current practice is described and certain problems arising from this are discussed.
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Ecotoxicol Environ Saf
January 2025
Department of Forensic Medicine, School of Forensic Medicine, Kunming Medical University, Kunming, China. Electronic address:
Mushroom poisoning, predominantly caused by α-amanitin, is a critical food safety concern in worldwide, with severe cases leading to hepatotoxicity and fatalities. This study delves into the hepatotoxic effects of α-amanitin, focusing on the NLRP3 inflammasome and PPAR-γ's regulatory role in inflammation. In vitro studies with L-02 cells showed that α-amanitin reduces cell viability and triggers NLRP3 inflammasome activation, increasing NF-κB phosphorylation and pro-inflammatory cytokines IL-18 and IL-1β.
View Article and Find Full Text PDFViruses
January 2025
School of Medical, Molecular and Forensic Sciences, College of Environmental and Life Sciences, Murdoch University, 90 South Street, Perth 6150, Australia.
is a terrestrial orchid endemic to southwestern Australia. The virus status of has not been studied. Eighty-three samples from 16 populations were collected, and sequencing was used to identify RNA viruses from them.
View Article and Find Full Text PDFChildren (Basel)
January 2025
Department of Dentistry, Faculty of Medicine and Pharmacy, University of Oradea, 10 Piața 1 Decembrie Street, 410073 Oradea, Romania.
Background/objectives: Dental age estimation plays a critical role in pediatric dentistry, orthodontics, and forensic medicine. The Nolla method, widely applied globally, has shown variable accuracy across different populations. This study aimed to evaluate the applicability and accuracy of the Nolla method in estimating the dental age of Romanian children and to identify potential discrepancies between dental and chronological ages.
View Article and Find Full Text PDFHealthcare (Basel)
January 2025
Department of Nursing, School of Medicine, Kurume University, 777-1 Higashikushiharamachi, Kurume-Shi 830-0003, Fukuoka, Japan.
Background/objectives: This study aimed to identify factors associated with harmful behavior toward others based on existing research.
Methods: This scoping review focused on individuals at risk of harming others due to mental health issues, with the target population encompassing three settings: the community, inpatient facilities with frequent admissions and discharges, and healthcare settings where medical treatment is sought. A scoping review was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews.
J Transl Med
January 2025
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, P. R. China.
Background: The high mortality rate of metastatic colorectal cancer (CRC) is primarily attributed to resistance to chemotherapy, where cancer stem cells (CSCs) play a crucial role. Deubiquitinating enzymes are essential regulators of CSC maintenance, making them potential targets for eliminating CSCs and overcoming chemotherapy resistance. This study aims to identify key deubiquitinating enzymes regulating CSCs and drug resistance of CRC.
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