[Bone metastasis in patients with breast cancer].

Breast cancer (BC) is quite often accompanied by affection of the bones and alterations in mineral metabolism. The most important clinical manifestations of the above processes that appeared to a considerable extent to be a cause of a poor condition of patients include pains in bones, pathological fracture and hypercalcemia. Metastatic events in the skeleton bone are recordable in 13.5 to 85 percent of cases, as evidenced by autopsy findings. In BC patients presenting with hormone-dependent tumours and metastases in the bones, indices for survival tend to be much higher than in those patients with solid tumours of other localization. The higher level of survival in such patients warrants an effective palliative treatment to be instituted to improve quality of their lives.