[The reconstruction of neovascularization of posterior pharyngeal flap: an experimental study in dogs].

Zhonghua Zheng Xing Wai Ke Za Zhi

Department of Oral and Maxillofacial Surgery, Faculty of Stomatology, Xiang Ya Hospital, Central South University, Changsha 410078, China.

Published: March 2003

AI Article Synopsis

  • The study investigated how neovascularization (new blood vessel formation) develops in two types of posterior pharyngeal flap surgeries in dogs, comparing superior and inferior flap placements.
  • The results showed that the superiorly based flaps demonstrated quicker blood vessel reconstruction, forming a mature network within 30 days, while inferiorly based flaps took longer to develop a mature network, reaching that stage by 90 days.
  • Both flap types were ultimately able to establish a sufficient blood supply through their vascular networks, but their timelines for maturation differed significantly.

Article Abstract

Objective: To elucidate the reconstruction of neovascularization that occurred in the superiorly and inferiorly based posterior pharyngeal flaps in different time postoperatively.

Methods: Ten mongrel dogs were randomly divided into two experimental groups, which were performed superiorly or inferiorly based posterior pharyngeal flap surgery respectively. Each group was then subdivided into five subgroups, and were sacrificed immediately after operation or on 3, 7, 30, 90 day postoperative respectively. Microangiography was used to exhibite the vessel.

Results: 1. The blood vessel reconstruction of the superiorly based posterior pharyngeal flap was more rapid compared with the inferiorly based flap. The 3-day flap has established an axial vascular network, which was mature on the 30-day flap. The superiorly based posterior pharyngeal flap was mainly supplied by the pedicle. 2. The blood vessels reconstruction of the inferiorly based posterior pharyngeal flap was firstly occurred in the pedicle and apex of the flap, which grew slowly to the middle of the flap. The inferiorly based posterior pharyngeal flap was supplied by the pedicle and the soft palate. A mature axial vascular network was exhibited on the 90-day flap, which was not mature on the 30-day flap.

Conclusion: Both superiorly and inferiorly based posterior pharyngeal flap can establish an axial vascular network and gain ample blood supply.

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