The 1998 Boyer Commission Report advocated improvement of undergraduate education at large research universities through large-scale participation of undergraduates in the universities' research mission. At a recent conference sponsored by the Reinvention Center, which is dedicated to furthering the goals of the Boyer Commission, participants discussed progress toward these goals and recommendations for future action. A breakout group representing the life sciences concluded that independent research experience for every undergraduate may not be feasible or desirable but that transformation of lecture courses to more inquiry-based and interactive formats can effectively further the Commission's goals.
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| http://dx.doi.org/10.1187/cbe.03-02-0004 | DOI Listing |
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Microvascular Inflammation of Kidney Allografts and Clinical Outcomes.
N Engl J Med
October 2024
From Université Paris Cité, INSERM Unité 970, Paris Institute for Transplantation and Organ Regeneration (M.S., A.S., M. Raynaud, V.G., G.D., D.Y., J.H., C. Legendre, O.A., C. Lefaucheur, A.L.), the Department of Pathology, Bichat Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP) (A.S.), the Kidney Transplant Department (G.D., C. Lefaucheur) and the Department of Pathology (J. Verine), Saint-Louis Hospital, AP-HP, the Department of Pathology, Necker Hospital, AP-HP (M. Rabant), the Division of Pediatric Nephrology, Necker Hospital, AP-HP, Université Paris Cité (O. Boyer), the Department of Kidney Transplantation, Necker Hospital, AP-HP (M.T., C. Legendre, D.A., O.A., A.L.), and the Division of Pediatric Nephrology, Robert Debré Hospital, AP-HP (J.H.), Paris, the Departments of Pediatric Nephrology (M.F.) and Nephrology (M.L.Q.), Centre Hospitalier Universitaire (CHU) Montpellier, Montpellier, the Pediatric Nephrology Department, Hôpital Universitaire Mère-Enfant, Hospices Civils de Lyon (HCL) (A.-L.S.-L.), and the Department of Transplantation, Edouard Herriot University Hospital, HCL, University of Lyon I (E.M.), Lyon, the Department of Nephrology-Dialysis-Transplantation, CHU de Toulouse, Toulouse (A.B., N.K.), Nantes Université, CHU Nantes, INSERM, Center for Research in Transplantation and Translational Immunology, Unité Mixte de Recherche 1064, Institute of Urology-Nephrology Transplantation of the University Hospital of Nantes, Nantes (R.D., M.G., P.-A.G., S.B.), and the Departments of Pathology (B.C.) and Nephrology, Transplantation, Dialysis, and Apheresis (L.C.), CHU Bordeaux, Bordeaux - all in France; the Division of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health (B.C.A.), and the Department of Pathology, University of Wisconsin (A.A., W.Z.) - both in Madison; Pediatric Nephrology, David Geffen School of Medicine at UCLA, UCLA Mattel Children's Hospital (P.W.), and Cedars-Sinai Comprehensive Transplant Center (E.H.) - both in Los Angeles; the Department of Pediatrics, University of Washington School of Medicine, Seattle Children's Hospital, Seattle (J.S.); the Division of Pediatric Nephrology, Emory University School of Medicine, Children's Pediatric Institute, Atlanta (R.G.); the Division of Pediatric Nephrology, University of Kansas City, Children's Mercy Hospital, Kansas City, MO (B.A.W.); the Division of Pediatric Nephrology and Hypertension, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis (R.S.Z.); the Acute Dialysis Units, Pediatric Kidney Transplant, Medical University of South Carolina, Charleston (K.T.); the Division of Pediatric Nephrology, Hypertension, and Apheresis, Washington University School of Medicine and St. Louis Children's Hospital, St. Louis (V.R.D., R.S.D.); the Department of Pediatrics, Robert Wood Johnson Medical School at Rutgers University, New Brunswick, NJ (V.R.D.); the Department of Pediatrics I, University Children Hospital Heidelberg, Heidelberg (B.T.), and the Department of Nephrology and Critical Care Medicine, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Berlin Institute of Health, Berlin (R.A.C., K.B.) - both in Germany; the Division of Abdominal and Transplantation Surgery, Department of Surgery, Faculty of Medicine, Geneva University Hospitals (T.B.), and the Division of Transplantation Immunology, University Hospital of Geneva (J. Villard), Geneva, and the Division of Clinical Pharmacology, Department of Medicine, and the Department of Laboratory Medicine and Pathology, Lausanne University Hospital, Faculty of Medicine, University of Lausanne, Lausanne (F.R.G.) - all in Switzerland; and the Department of Nephrology and Kidney Transplantation, Vall d'Hebrón University Hospital, Barcelona (O. Bestard).
Background: The heterogeneous clinical presentation of graft microvascular inflammation poses a major challenge to successful kidney transplantation. The effect of microvascular inflammation on allograft outcomes is unclear.
Methods: We conducted a cohort study that included kidney-transplant recipients from more than 30 transplantation centers in Europe and North America who had undergone allograft biopsy between 2004 and 2023.
Individual genotypes from environmental DNA: Fingerprinting snow tracks of three large carnivore species.
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Université Grenoble Alpes, Université Savoie Mont Blanc, CNRS, LECA, Laboratoire d'Ecologie Alpine, Grenoble, France.
Continued advancements in environmental DNA (eDNA) research have made it possible to access intraspecific variation from eDNA samples, opening new opportunities to expand non-invasive genetic studies of wildlife populations. However, the use of eDNA samples for individual genotyping, as typically performed in non-invasive genetics, still remains elusive. We present successful individual genotyping of eDNA obtained from snow tracks of three large carnivores: brown bear (Ursus arctos), European lynx (Lynx lynx) and wolf (Canis lupus).
View Article and Find Full Text PDFEconomic impact of reducing treatment gaps in depression.
Eur Psychiatry
June 2023
Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Background: Major depressive disorder (MDD) is highly prevalent across Europe. While evidence-based treatments exist, many people with MDD have their condition undetected and/or untreated. This study aimed to assess the cost-effectiveness of reducing treatment gaps using a modeling approach.
View Article and Find Full Text PDF[From transfer to transition: review and proposition of the SFNDT dialysis Commission].
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Centre universitaire des maladies rénales, CHU de Caen, Avenue de la côte de Nacre, 14033 Caen Cedex 9, France
Over the course of their disease, patients with chronic kidney disease (CKD) will be treated by several kidney replacement therapy (KRT) modalities. The transitions between KRT modalities can be experienced as traumatic by patients, and are associated with an increased morbidity and mortality, notably when they are not anticipated. Planning these transition phases could reduce the psychological trauma induced by the transfer, as well as reduce the risk of morbidity and mortality.
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Eur Psychiatry
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Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
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