[Detection of carriers of hemophilia B].

Cas Lek Cesk

Ustav hematologie a krevní transfúze, Praha.

Published: December 1992

Thirty-two families with haemophilia B were divided into sub-groups based on assessment of fIX:Ag, fIX:C and the thromboplastin time with bovine thromboplastin. In confirmed carriers from these families after assessment of fIX:Ag and, fIX:C the normal range of individual sub-groups of confirmed carriers was assessed and compared with values of fiX:Ag and fiX:C of the control group. It will be possible to use these groups after their extension to assess probable carriers in sub-groups CRM+ and CRM-. In the sub-group CRMR the only criterium of transmission is a reduced fIX:C level. A prolonged TP with bovine thromboplastin in families with BM haemophilia cannot be used to assess carriers.

Download full-text PDF

Source

Publication Analysis

Top Keywords

fixag fixc
12
families haemophilia
8
assessment fixag
8
bovine thromboplastin
8
confirmed carriers
8
[detection carriers
4
carriers hemophilia
4
hemophilia thirty-two
4
thirty-two families
4
haemophilia divided
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!