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September 14, 2024 was the 100th anniversary of the birth of a major scientist, specialist in the field of medical climatology, clinical physiology of respiration and circulation, Honored Scientist of the Ukrainian SSR, Doctor of Medical Sciences, Professor Vyacheslav Georgievich Boksha (14.09.1924-22.

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Importance: The drug HD201 is a biosimilar candidate for breast cancer treatment as the reference trastuzumab.

Objective: To compare the efficacy of HD201 with referent trastuzumab.

Design, Setting, And Participants: This randomized clinical trial (TROIKA) included 502 women with ERBB2-positive early breast cancer treated with either HD201 or referent trastuzumab.

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[Professor V.G.Korenchevsky - scientist, patriot, passionary.].

Adv Gerontol

July 2021

S.M.Kirov Military Medical Academy, 6 Acad. Lebedev str., St. Petersburg 194044, Russian Federation, e-mail:

The article is devoted to the life and work of the Russian-British scientist, Professor of the Imperial Military Medical Academy in Saint-Peterburg and Head of the Oxford Gerontological Research Unit, Vladimir Georgievich Korenchevsky. Among the scientific achievements of V.G.

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The article summarizes the findings of Russian and international studies of the genetic aspects of polygenic urolithiasis associated with impairment of calcium metabolism. The article analyzes the genetic risk factors of polygenic nephrolithiasis that show significant association with the disease in case-control studies and Genome-Wide Association Studies (16 genes). We described the gene functions involved in concrement formation in polygenic nephrolithiasis.

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