Enhanced production of recombinant B-domain deleted factor VIII from Chinese hamster ovary cells by propionic and butyric acids.

Biotechnol Lett

Department of Agricultural Chemistry, College of Life and Environmental Sciences, Korea University, 5 Ga Anamdong, Sungbook-gu, Seoul 136-075, Korea.

Published: February 2003

Sodium propionate, as well as sodium butyrate, enhanced the production of recombinant B-domain-deleted, factor VIII (rFVIIIdB) by Chinese hamster ovary cells growing in a spinner-flask with a protein-free medium by more than six-fold. The two acids, however, had different cytotoxicities.

Download full-text PDF

Source
http://dx.doi.org/10.1023/a:1022301528118DOI Listing

Publication Analysis

Top Keywords

enhanced production
8
production recombinant
8
factor viii
8
chinese hamster
8
hamster ovary
8
ovary cells
8
recombinant b-domain
4
b-domain deleted
4
deleted factor
4
viii chinese
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!