AI Article Synopsis
- Phospholipids are crucial parts of biological membranes but are challenging to identify and quantify without chemical modification.
- Chemical derivatization enhances the detection and measurement of phospholipids in biological samples.
- The paper reviews various derivatization techniques for phospholipids used in HPLC, CE, and GC, along with historical methods for TLC.
Article Abstract
Phospholipids are major components of biological membranes. Without chemical derivatization, it is difficult to identify and quantitate phospholipids in biological samples. Chemical derivatization can improve both the selectivity and sensitivity of the analytes. This paper gives a full review, through March, 2002, of derivatization methods used for phospholipids in HPLC, CE and GC as well as the spray reagent used for TLC in the early days.
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| http://dx.doi.org/10.1016/s1570-0232(03)00359-3 | DOI Listing |
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