In popular articles that play down the genetical differences among human populations, it is often stated that about 85% of the total genetical variation is due to individual differences within populations and only 15% to differences between populations or ethnic groups. It has therefore been proposed that the division of Homo sapiens into these groups is not justified by the genetic data. This conclusion, due to R.C. Lewontin in 1972, is unwarranted because the argument ignores the fact that most of the information that distinguishes populations is hidden in the correlation structure of the data and not simply in the variation of the individual factors. The underlying logic, which was discussed in the early years of the last century, is here discussed using a simple genetical example.
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http://dx.doi.org/10.1002/bies.10315 | DOI Listing |
Handb Clin Neurol
March 2025
Laboratoire de Psychologie Cognitive, CNRS, Aix-Marseille University, Institute of Language, Communication and the Brain, Marseille, France.
A majority of humans are right-handed and exhibit left hemisphere specialization for the comprehension and production of language. To what extent population-level behavioral and brain asymmetries are unique to humans remains a topic of interest across a wide range of scientific disciplines. In this chapter, we present current findings on the expression of population-level behavioral and brain asymmetries in nonhuman primates.
View Article and Find Full Text PDFZhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Ophthalmology, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Objectives: Due to the severe shortage of donor corneas for transplantation in China, corneal component transplantation may expand the available donor pool. This study aims to evaluate the safety and feasibility of corneal component transplantation by examining the distribution of hepatitis B surface antigen (HBsAg) in corneas from HBsAg-seropositive donors under different storage media.
Methods: Ten corneas (from 6 donors) donated between December 2019 and March 2021 and stored at the Eye Bank of Xiangya Third Hospital, Central South University, were analyzed.
Hamostaseologie
March 2025
Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva and Institute of Genetics and Genomics in Geneva (iGE3), Geneva, Switzerland.
Congenital fibrinogen deficiencies (CFDs), traditionally considered rare monogenic disorders, are now recognized as more prevalent and genetically complex than previously thought. Indeed, the symptoms manifested in CFD patients, such as bleeding and thrombosis, are likely to result from variation in several genes rather than solely driven by variants in one of the three fibrinogen genes, , , and . This review highlights recent advances in understanding the genetic causes of CFD and their variability, facilitated by the growing use and availability of next-generation sequencing data.
View Article and Find Full Text PDFAm J Obstet Gynecol
March 2025
Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Background: Using menstrual products is a part of managing menstrual bleeding. Products use may represent individual, social, and economic influences. A few studies on menstrual product use from specific regions in the United States (US) reported differences in use across demographic factors like age and race and ethnicity.
View Article and Find Full Text PDFExp Clin Endocrinol Diabetes
March 2025
Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
The impact of different drinking solutions used for an oral glucose tolerance test (oGTT) on 2-h glucose values and gastrointestinal side effects are not clear. This study compared a commercially produced solution (Accu-Chek Roche solution) and a standardized pharmacy solution (NRF 13.8.
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