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Crystallization and preliminary crystallographic analysis of DJ-1, a protein associated with male fertility and parkinsonism. | LitMetric

Crystallization and preliminary crystallographic analysis of DJ-1, a protein associated with male fertility and parkinsonism.

Acta Crystallogr D Biol Crystallogr

Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.

Published: August 2003

AI Article Synopsis

Article Abstract

DJ-1 was identified as a novel oncogene product that transformed mouse NIH3T3 cells in cooperation with activated Ras. DJ-1 was also correlated with male infertility and parkinsonism. DJ-1 was crystallized using sodium citrate and HEPES at pH 7.5. The crystal belongs to space group P3(1) or P3(2), with unit-cell parameters a = 75.04, c = 74.88 A and contains two molecules in an asymmetric unit. An intensity data set was collected to 2.00 A resolution.

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Source
http://dx.doi.org/10.1107/s090744490301271xDOI Listing

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