A total of 111 patients with myocardial infarction were studied in the early, period of the disease. Exercise and information load tests, impedance plethysmography, electrocardiography, and large-framed fluorography were performed. Among the patients with myocardial infarction who responded to information load by exhibiting transient silent ischemia, vasospastic reactions were demonstrated to be diagnosed mainly in those with posterior myocardial infarction. The patients with anterior myocardial infarction responded to psychoemotional stress mainly by showing ischemia formed under the conditions of higher myocardial oxygen uptake due to increased blood minute volume. In most patients, the area of silent psychogenic vasospastic ischemia coincided with that of infarct-related myocardium, whereas ischemic changes were largely located in the anterior left ventricular wall despite the area of myocardial necrosis when psychogenic ischemia developed with increased myocardial oxygen uptake.
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Medicine (Baltimore)
January 2025
Zhengzhou Central Hospital Affiliated to Zhengzhou University, Henan, China.
Inflammatory responses and lipid metabolism disorders are key components in the development of coronary artery disease and contribute to no-reflow after coronary intervention. This study aimed to investigate the association between the neutrophil to high-density lipoprotein ratio (NHR) and no-reflow phenomenon in ST-segment elevation myocardial infarction (STEMI) patients after primary percutaneous coronary intervention (PPCI). This study enrolled 288 patients with STEMI from September 1st, 2022 to February 29th, 2024, in the Zhengzhou Central Hospital Affiliated to Zhengzhou University.
View Article and Find Full Text PDFPLoS One
January 2025
Nursing & Midwifery Research Department (NMRD), Hamad Medical Corporation, Doha, Qatar.
Background: Ischemic heart disease (IHD) has a significant impact on public health and healthcare expenditures in the United States (US).
Methods: We used data from the CDC WONDER database from 1999-2020 to identify trends in the IHD-related mortality of patients ≥ 75 years in the US. AAMRs per 100,000 population and APC were calculated and categorized by year, sex, race, and geographic divisions.
Adv Sci (Weinh)
January 2025
Shanghai Key Laboratory of Vascular Lesions and Remodeling, Department of Vascular Surgery, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, 201399, China.
Acute myocardial infarction (AMI) is associated with well-established metabolic risk factors, especially hyperlipidemia and obesity. Myocardial ischemia-reperfusion injury (mIRI) significantly offsets the therapeutic efficacy of revascularization. Previous studies indicated that disrupted lipid homeostasis can lead to lipid peroxidation damage and inflammation, yet the underlying mechanisms remain unclear.
View Article and Find Full Text PDFEur Radiol
January 2025
Hôpital Privé Jacques Cartier, Institut Cardiovasculaire Paris Sud (ICPS), Ramsay-Santé, 91300, Massy, France.
Objectives: To determine whether plaque composition analysis defined by cardiac CT can provide incremental prognostic value above coronary artery disease (CAD) burden markers in symptomatic patients with obstructive CAD.
Materials And Methods: Between 2009 and 2019, a multicentric registry included all consecutive symptomatic patients with obstructive CAD (at least one ≥ 50% stenosis on CCTA) and was followed for major adverse cardiovascular (MACE) defined by cardiovascular death or nonfatal myocardial infarction. Each coronary segment was scored visually for both the degree of stenosis and composition of plaque, which were classified as non-calcified, mixed, or calcified.
Toxics
December 2024
Intensive Careful Unit, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315040, China.
Cardiovascular disease continues to be a major contributor to global morbidity and mortality, with environmental and occupational factors such as air pollution, noise, and shift work increasingly recognized as potential contributors. Using a two-sample Mendelian randomization (MR) approach, this study investigates the causal relationships of these risk factors with the risks of unstable angina (UA) and myocardial infarction (MI). Leveraging single nucleotide polymorphisms (SNPs) as genetic instruments, a comprehensive MR study was used to assess the causal influence of four major air pollutants (PM, PM, NO, and NO), noise, and shift work on unstable angina and myocardial infarction.
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