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Gut fungal profile in new onset treatment-naïve ulcerative colitis in Saudi children.
Saudi J Gastroenterol
January 2025
Department of Pediatrics (Gastroenterology Unit), College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Background: Although the role of fungi in gut inflammation in IBD has been suggested, data are still limited in ulcerative colitis (UC). Our aim was to describe the gut fungal profile in a pediatric UC in Saudi Arabia.
Methods: Fecal samples from children with UC and control samples provided by healthy school children were collected.
Differential intestinal microbes and metabolites between Behcet's uveitis and Fuchs syndrome.
Heliyon
October 2024
Ophthalmologic Center of the Second Hospital, Jilin University, Ziqiang Street 218, Changchun, PR China.
Objective: Behcet's uveitis (BU) is a type of uveitis with a high rate of blindness, characterized by anterior segment inflammation, vitreous opacity, and retinal vasculitis. Its pathogenesis is still unclear. Fuchs syndrome (Fuchs) is another common type of uveitis, which clinically presents with anterior segment inflammation and vitreous opacity, but rarely causes blindness.
View Article and Find Full Text PDFWashed microbiota transplantation via colonic transendoscopic enteral tube rescues severe acute pancreatitis: A case series.
Heliyon
July 2024
Gastroenterology, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, China.
Background: Gut microbiota dysbiosis plays a significant role in the development of acute pancreatitis (AP). However, a recent randomized trial reported negative findings regarding the use of fecal microbiota transplantation (FMT) via the mid-gut tube in severe AP. The case series presents the feasibility of washed microbiota transplantation (WMT) as a new methodology of FMT and its delivery via colonic transendoscopic enteral tubing (TET) for severe AP.
View Article and Find Full Text PDFFaecal biomarkers for diagnosis and prediction of disease course in treatment-naïve patients with IBD.
Aliment Pharmacol Ther
September 2024
Department of Medical Sciences, Gastroenterology Research Group, Uppsala University, Uppsala, Sweden.
Article Synopsis
- Faecal biomarkers are significant for assessing inflammatory bowel disease (IBD), with the study focusing on their role in diagnosing and predicting disease progression.
- The study included 65 Crohn's disease patients, 90 ulcerative colitis patients, symptomatic controls, and healthy controls, analyzing various biomarkers in faecal samples.
- Key findings showed that calprotectin and myeloperoxidase were the most accurate in distinguishing IBD from other groups, and their levels could predict an aggressive disease course, especially with myeloperoxidase showing the strongest association.
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