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[Reactive Perforating Collagenosis in Hemodialysis Patients].

G Ital Nefrol

October 2024

Presidio Ospedaliero Maria SS Addolorata Eboli, U.O.C. di Nefrologia e Dialisi.

Chronic Kidney Disease associated Pruritus (CKD-aP) in hemodialysis affects approximately 38% of our patients. It is not associated with any dermatological lesion other than the common scratching lesions, a consequence of the symptom itself. The causes associated with itching have been studied in various treatments.

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Article Synopsis
  • Reactive perforating collagenosis (RPC) is a rare skin condition where collagen breaks through the skin, leading to various symptoms, including bumps and crusting lesions.
  • It's linked to systemic diseases like diabetes and autoimmune disorders, with its causes involving abnormal collagen metabolism and environmental factors.
  • Treatment focuses on addressing underlying conditions and symptom relief through topical medications, with patient outcomes improving through early diagnosis and ongoing research.
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Thoracoscopic pericardial fenestration for effective long-term management of non-tuberculous mycobacterium pericarditis.

Gen Thorac Cardiovasc Surg

January 2015

Department of Thoracic, Endocrine Surgery and Oncology, Institute of Health Bioscience, University of Tokushima Graduate School, Kuramoto-cho 3-18-15, Tokushima, 770-8503, Japan.

The long-term consequences of non-tuberculous mycobacterium pericarditis with pericardial effusion after fenestration have not been described. We encountered a case of non-tuberculous mycobacterium pericarditis in a 59-year-old woman with an underlying collagenosis. Repeated drainage was required because of rapid reaccumulation of the effusion.

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Background: Dilated cardiomyopathy (DCM) is a heart muscle disease that is endemic in Africa. Over the past 50 years, South African investigators have made significant contributions to scientific elucidation of the condition. The objective of this review was to summarise their research on the subject of DCM.

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Sirolimus is an immunosuppressive macrolide with antineoplasic properties that is increasingly used in posttransplantation immunosuppression. The treatment is frequently associated with cutaneous side effects such as sirolimus-associated acneiform facial dermatitis, which has been observed in up to 50% of treated patients. We report a 51-year-old female with liver transplantation who developed inflammatory papules and nodules on the face and the upper chest 3 weeks after the initiation of sirolimus therapy.

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