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J Vet Med Sci
January 2025
Laboratory of Veterinary Pathology, School of Veterinary Medicine, Azabu University.
This report describes an atypical case of canine acanthomatous ameloblastoma (CAA) with mucinous glandular differentiation in a 12-year-old male Chihuahua with a right mandibular mass. Initially diagnosed as CAA by biopsy, computed tomography revealed bone lysis, prompting surgical excision. Histological examination showed lobular growth with two distinct neoplastic cell populations: typical CAA-like cells and a minor glandular structure population.
View Article and Find Full Text PDFCureus
November 2024
Oral and Maxillofacial Surgery, Burdwan Dental College and Hospital, Burdwan, IND.
Peripheral ameloblastoma is a rare, benign, slow-growing odontogenic neoplasm prevalent in the mandible. It originates from the odontogenic epithelium and its remnants, and its histological characteristics are identical to those of intraosseous ameloblastoma. It is less aggressive and invasive than its intraosseous variety, with a low recurrence rate.
View Article and Find Full Text PDFCureus
November 2024
Otolaryngology and Head and Neck Surgery, Kobe City Medical Center General Hospital, Kobe, JPN.
This report presents a notable approach to treating a locally invasive maxillary ameloblastoma in a 46-year-old woman using an endoscopy-assisted total maxillectomy via a contralateral transmaxillary approach without a subciliary incision. Ameloblastomas, though benign, require radical surgical management due to their aggressive nature and high recurrence rates, especially in the maxilla. Traditional techniques often involve extensive facial incisions, leading to significant scarring and potential complications.
View Article and Find Full Text PDFHeliyon
December 2024
Department of Oral and Maxillofacial Surgery, Showa University School of Dentistry, Tokyo 145-8515, Japan.
Pulmonary metastasis of ameloblastoma is a rare associated with the histopathologically plexiform types of ameloblastoma. In this report, we present an exceptionally rare case of pulmonary metastatic ameloblastoma without local recurrence, emerging 12 years post-initial resection. A female patient, initially diagnosed with mandibular desmoplastic ameloblastoma, revealed masses in both lung fields of the lung on chest radiography, while chest computed tomography revealed more than 10 nodules in both lungs.
View Article and Find Full Text PDFHead Neck Pathol
December 2024
Institute of Pathology, Sheba Medical Center, Tel Hashomer, 5265601, Israel.
Purpose: Current standard of care for ameloblastoma (conventional/unicystic - mural type) usually mandates extensive bone resection that frequently necessitates immediate reconstruction with serious sequelae, especially among young patients. BRAF-mutated ameloblastomas can be targeted by BRAF inhibitors to markedly reduce their size, enabling conservative removal of residual tumor. We aimed to characterize the effect of post-treatment histomorphologic changes.
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