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Gastric myeloid sarcoma mimicking pseudoachalasia in non-leukemic context: a singular case report.
Ann Med Surg (Lond)
April 2024
Faculty of Medicine, Palestine Polytechnic University, Hebron, Palestine.
Introduction And Importance: Myeloid sarcoma (MS) is a rare tumour associated with acute myeloid leukaemia (AML) and occasionally occurs independently. It typically affects skin, bone, lymph nodes, and rarely the gastrointestinal tract, with gastric cases being extremely rare. Notably, no reported instances associate pseudoachalasia with gastric myeloid sarcoma.
View Article and Find Full Text PDFVascular Disruptive Hydrogel Platform for Enhanced Chemotherapy and Anti-Angiogenesis through Alleviation of Immune Surveillance.
Pharmaceutics
August 2022
Department of Neurology, The Fifth Affiliated Hospital of Jinan University, Jinan University, Heyuan 517000, China.
Patients undergoing immunotherapy always exhibit a low-response rate due to tumor heterogeneity and immune surveillance in the tumor. Angiogenesis plays an important role in affecting the status of tumor-infiltrated lymphocytes by inducing hypoxia and acidosis microenvironment, suggesting its synergistic potential in immunotherapy. However, the antitumor efficacy of singular anti-angiogenesis therapy often suffers from failure in the clinic due to the compensatory pro-angiogenesis signaling pathway.
View Article and Find Full Text PDFDiffuse leptomeningeal glioneuronal tumor in a Chinese adult: a novel case report and review of literature.
Acta Neurol Belg
April 2020
Department of Functional Neurosurgery, The Brain Hospital Affiliated to Nanjing Medical University, Nanjing, 210029, China.
Diffuse leptomeningeal glioneuronal tumor (DLGNT) is a rare glioma tumor classified by the World Health Organization as a central nervous system tumor in 2016. DLGNT is most common in children and adolescents but is rare in adults. A 25-year-old male patient was admitted due to recurrent seizures.
View Article and Find Full Text PDFSingular case of osteolytic lesions revealing transformation of myeloproliferative syndrome to acute leukemia.
Joint Bone Spine
March 2019
Service de rhumatologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France; Groupe d'Eudes Remodelage Osseux et bioMatériaux LHEA UPRES EA 4658, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France. Electronic address:
Hematological malignancies can cause bone lesions, of which the most common are the punched-out foci of osteolysis seen in multiple myeloma. However, osteosclerotic lesions are more common in myeloproliferative disorders. We report the unusual case of a patient with myeloproliferative syndrome in whom the development of osteolytic lesions revealed transformation to acute leukemia.
View Article and Find Full Text PDFShort-Spindled Cell Haemangioblastoma with CD34 Expression: New Histopathological Variant or Just a Stochastic Cytological Singularity?
Case Rep Pathol
June 2016
Pathology Unit, Neuropathology Service, Mexico General Hospital, 06726 Cuauhtémoc, DF, Mexico.
Haemangioblastomas are neoplasms of uncertain histogenesis with cellular and reticular variants advocated in current lore. Herein we describe an intriguing cerebellar specimen with unusual traits including spindle cell morphology and CD34 positivity. A thirty-nine-year old man had an infratentorial tumour discovered incidentally and resected three times.
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