Bilateral combined retinal and choroidal detachment in antineutrophil cytoplasmic antibody-positive scleritis.

Acta Ophthalmol Scand

Birmingham and Midland Eye Centre, City Hospital NHS Trust, Birmingham B18 7QU, UK.

Published: August 2003

Purpose: To describe a rare complication of scleritis in a patient with positive serum antineutrophil cytoplasmic antibodies (ANCA).

Methods: We present a case report of a patient who developed bilateral retinal and choroidal detachment associated with ANCA-positive scleritis.

Results: Oral steroids alone were insufficient to maintain sustained remission of ocular inflammation. Clinical relapse of the scleritis was associated with ANCA titres becoming positive again. A combination of cyclophosphamide and steroids was successful in achieving control of the intraocular inflammation over a follow-up period of 18 months.

Conclusion: Bilateral combined retinal and choroidal detachment is a potentially blinding complication of ANCA-positive scleritis. Monitoring of ANCA titres is useful in the management of the disease.

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http://dx.doi.org/10.1034/j.1600-0420.2003.00083.xDOI Listing

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