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Background: Osteoarthritis (OA) of the knee is a prevalent chronic degenerative joint condition that is having a growing impact on a global scale., posing a challenge in diagnosis which is often reliant on time-consuming and error-prone visual analysis by physicians. There is a critical need for an automated, efficient, and accurate diagnostic method to improve early detection and treatment.

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Enteric fever is caused by Salmonella typhi and Salmonella paratyphi A and B, which can present clinically with variety of symptoms. We report a case of a middle-aged gentleman with salmonella infection who developed reversible corpus callosum splenium infarcts, which is an unusual presentation of enteric fever. The condition was reversed with antibiotics routinely used to treat enteric fever in the country.

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Etiology, histology, and long-term outcome of bilateral testicular regression: a large Belgian series.

Hum Reprod Open

December 2023

Department of Internal Medicine and Pediatrics, Ghent University, Pediatric Endocrinology Service, Ghent University Hospital, Belgium, Ghent.

Article Synopsis
  • - The study investigates the long-term effects of bilateral testicular regression (BTR) in individuals, focusing on growth and development outcomes, particularly highlighting suboptimal penile growth often related to genetic factors.
  • - BTR, a rare condition with potential vascular and genetic origins, was analyzed in a cross-sectional study involving 35 participants recruited from eight pediatric endocrinology departments in Belgium over three years.
  • - Key findings revealed common maternal complications during pregnancy and identified specific genetic variants in some participants, while a centralized review of gonadal tissue contributed to understanding the condition's clinical implications.
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Enhanced neurobiological biomarker differentiation for attention-deficit/hyperactivity disorder through a risk-informed design.

Eur Child Adolesc Psychiatry

December 2024

Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Article Synopsis
  • * Researchers analyzed data from 2,511 children and adolescents in Brazil, comparing ADHD biomarkers like polygenic scores, subcortical volumes, and executive function among different risk groups.
  • * Findings showed that a risk-informed approach significantly highlighted differences in biomarkers, suggesting this method could improve evaluations for ADHD and potentially other mental disorders.
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Background: Innovative algorithms for wearable devices and garments are critical for diagnosing and monitoring disease (such as lateral epicondylitis (LE)) progression. LE affects individuals across various professions and causes daily problems.

Methods: We analyzed signals from the forearm muscles of 14 healthy controls and 14 LE patients using high-density surface electromyography.

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