AI Article Synopsis
- A new group of compounds called 2-arylpyrimidin-4-ones has been discovered and studied for their potential as CRF-1 receptor antagonists.
- These compounds have been synthesized and their chemical structure and activity have been analyzed.
- The compounds are structurally straightforward and show physical properties that are suitable for use in central nervous system (CNS) treatments.
Article Abstract
The discovery, synthesis and structure-activity studies of a novel series of 2-arylpyrimidin-4-ones as CRF-1 receptor antagonists is described. These compounds are structurally simple and display appropriate physical properties for CNS agents
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| http://dx.doi.org/10.1016/s0960-894x(03)00483-9 | DOI Listing |
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