AI Article Synopsis
- Recent reports highlight the benefits of valve-sparing surgery for patients with Marfan syndrome experiencing ascending aortic dissection.
- A 49-year-old woman with Marfan syndrome and a previous aortic repair faced sudden chest pain, leading to the discovery of a significant aortic dissection after an initial CT scan showed no issues.
- While her symptoms improved with treatment and she was discharged on anticoagulants, there are concerns that long-term anticoagulant use might worsen recurring dissections, suggesting valve-sparing procedures could be beneficial for such patients.
Article Abstract
Recent reports support the role of a valve-sparing procedure in ascending aortic dissection in patients with Marfans syndrome. A 49-year-old woman with Marfans syndrome and prior aortic aneurysm repaired with a composite graft presented with sudden-onset chest pain. Following an initial negative computed tomographic (CT) scan, a long dissection involving the descending thoracic and abdominal aorta was discovered on a repeat CT scan a few hours later. Symptoms improved gradually with optimal medical management and the patient was discharged home on anticoagulant therapy. Although no direct cause-and-effect relationship can be established, chronic anticoagulant therapy may accelerate the progression of recurrent dissection in these patients. A valve-sparing procedure should be considered in eligible patients with Marfans syndrome who need operative correction to avoid possible future untoward effects of long-term anticoagulant therapy.
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| http://dx.doi.org/10.1097/01.CRD.0000078443.08887.28 | DOI Listing |
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