Objective: To determine the intracranial tumor measurement reliability of three different magnetic resonance imaging machines.
Study Design: Neurofibromatosis Type 2 patients were imaged at three different facilities, two studies per facility, for a total of six studies per patient. Seven subjects were imaged.
Setting: Tertiary care center.
Patients: Neurofibromatosis Type 2 patients.
Outcome Measure: All tumors were measured by greatest diameter (in millimeters) and volume (in cubic centimeters). Schwannomas were measured in the anteroposterior and mediolateral dimensions (in millimeters), using the petrous ridge as an anatomic landmark.
Results: The reliability of magnetic resonance imaging measurement (greatest diameter, volume) of meningiomas and vestibular schwannomas were analyzed together. There were no statistically significant differences by magnetic resonance imaging machine. There was a trend for one scanner to produce greater differences between Test 1 and Test 2 than the other scanners. The minimal detectable change in tumor size for measuring greatest diameter and volume across scanners was calculated.
Conclusion: The minimal detectable change in greatest diameter (under the study acquisition protocol) was determined to be 1.1 mm. The minimal detectable change in volume (under the study acquisition protocol) was determined to be +/-0.15 cm(3). These results may be used when designing clinical trials using vestibular schwannoma or meningioma size changes as an outcome variable.
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http://dx.doi.org/10.1097/00129492-200307000-00022 | DOI Listing |
Background: Traumatic anterior shoulder dislocation is the most common type of joint dislocation, with an incidence of 11 to 29 per 100 000 persons per year. Controversy still surrounds the recommendations for treatment and the available procedures for surgical stabilization.
Methods: This review is based on pertinent publications (2014-2024) that were retrieved by a selective search in the PubMed and Google Scholar databases.
JAMA Neurol
January 2025
Department of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neurological Disorders, Beijing, China.
Importance: Autoantibodies targeting astrocytes, such as those against glial fibrillary acidic protein (GFAP) or aquaporin protein 4, are crucial diagnostic markers for autoimmune astrocytopathy among central nervous system (CNS) autoimmune disorders. However, diagnosis remains challenging for patients lacking specific autoantibodies.
Objective: To characterize a syndrome of unknown meningoencephalomyelitis associated with an astrocytic autoantibody.
Neth Heart J
January 2025
Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
The European Society of Cardiology (ESC) has updated its guidelines on cardiac pacing and cardiac resynchronisation. As the majority are class II recommendations (61%) and based on expert opinion (59%), a critical appraisal for the Dutch situation was warranted. A working group has been established, consisting of specialists in cardiology, cardiothoracic surgery, geriatrics, allied professionals in cardiac pacing, and patient organisations with support from the Knowledge Institute of the Dutch Association of Medical Specialists.
View Article and Find Full Text PDFJ Mol Neurosci
January 2025
Department II of Acupuncture and Moxibustion, Dongzhimen Hospital Beijing University of Chinese Medicine, No. 116, Cuiping West Road, Tongzhou District, Beijing, 101121, China.
The purpose of this study was to investigate the expression of miR-499a-5p in children with autism spectrum disorders (ASD) and its value in early diagnosis of ASD. This is a retrospective case-control study that included 40 children with ASD as a case group and 43 healthy children as a control group. Magnetic resonance imaging (MRI) was performed on all subjects, and the children were scored with childhood autism rating scale (CARS) and autism behavior checklist (ABC).
View Article and Find Full Text PDFAnn Surg Oncol
January 2025
Department of Surgery and Cancer, Imperial College London, London, UK.
Background: Early diagnosis of metastases is crucial but routine staging with contrast-enhanced multidetector computed tomography (ceMDCT) is suboptimal. A total of 20% will have indeterminate or too small to characterize (TSTC) liver lesions on CT, requiring formal characterization by magnetic resonance imaging (MRI). This UK cross-sectional study reports our experience undertaking routine abbreviated liver MRI (MRI).
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