Rapid infusion of sodium valproate in acutely ill children.

Angela K Birnbaum Robert L Kriel Shani K Norberg Beverly S Wical Duy N Le Ilo E Leppik James C Cloyd

Pediatr Neurol

Experimental & Clinical Pharmacology, Epilepsy Research and Education Program, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Published: April 2003

The purpose of this study was to investigate the clinical safety of sodium valproate and total and unbound valproic acid plasma concentrations after rapid infusion in hospitalized, acutely ill children. Four children (5-15 years) completed the study. Sodium valproate doses (8.3-15.4 mg/kg) were administered in

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http://dx.doi.org/10.1016/s0887-8994(03)00019-5	DOI Listing

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