Objective: To assess the prevalence of human T-cell lymphotropic virus type I and type II antibodies in blood donors donating blood for various reasons in a University hospital and to compare the results with other reports from the Kingdom of Saudi Arabia (KSA), and elsewhere.
Methods: A 7-year retrospective review of blood bank records for results of serological tests at the King Fahd Hospital of the University, Al-Khobar, KSA, from January 1995 to December 2001 was conducted. The study included review of blood donor questionnaire cards as well as extraction of any other relevant information.
Results: The results showed that the total number of blood donor units drawn during the 7- year period was 23493 units. A total of 50 units were found repeatedly reactive by enzyme immunoassay screening test (0.2%). Only 12 (0.05%) were confirmed reactive by western blot test and 4 were found to be indeterminate. Nine (0.04%) of the confirmed samples were from Saudi nationals. All 3 non-Saudi confirmed reactive donors were Indian nationals, while the 4 indeterminate cases, 2 were Saudis and 2 were Egyptians. A statistical estimate of the maximal risk of finding a positive donor in this donor population subgroup is in the order of 0.05%. The number of Saudi blood donors during this study was 16434 (80.3%) and non-Saudi donors was 4027 (19.7%).
Conclusion: Based on these results it is shown that the prevalence of this virus is still low among blood donors in the Eastern region of Kingdom of Saudi Arabia.
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J Transl Med
January 2025
Allen Institute for Immunology, Seattle, WA, USA.
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January 2025
Department of Medicine, Surgery and Neurosciences, Nephrology, Dialysis and Transplantation Unit, University Hospital of Siena, Siena, Italy.
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January 2025
Ophthalmology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli, 1, 00168, Rome, Italy.
Our objective is to determine the protein and complements constituents of Cord blood Platelet-rich plasma (CB-PRP), based on the hypothesis that it contains beneficial components capable of arresting or potentially decelerating the advancement of atrophic age-related macular degeneration (dry-AMD), with the support of radiomics. Two distinct pools of CB-PRP were assessed, each pool obtained from a total of 15 umbilical cord-blood donors. One aliquot of each pool respectively was subjected to proteomic analysis in order to enhance the significance of our findings, by identifying proteins that are shared between the two sample pools and gaining insights into the pathways they are associated with.
View Article and Find Full Text PDFAlzheimers Dement
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University of Michigan Medical School, Ann Arbor, MI, USA.
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Cancer Immunol Immunother
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Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital of Harbin Medical University, No. 246 Xuefu Road, Nangang District, Harbin, 150001, Heilongjiang Province, China.
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