AI Article Synopsis
- The study aimed to detect recurrences and metastases in colorectal cancer using a specific type of antibody imaging (111In-labeled B72.3).
- Fourteen patients were tested with different imaging techniques, where tomography proved to be more effective in distinguishing tumors and estimating their size compared to conventional imaging methods.
- The initial findings suggest that the Oncoscint CR-103 can be valuable for diagnosing colorectal carcinoma recurrences, assessing tumor viability post-radiotherapy, and informing surgical treatment decisions based on disease spread.
Article Abstract
Background/aims: The aim of the study is detection of the recurrences and metastases of colorectal carcinomas using 111In-labeled antibodies B72.3.
Methodology: Fourteen patients underwent planar immunoscintigraphy and/or tomoscintigraphy.
Results: With tomography in comparison to planar scintigraphy, we can access better distinction of tumor and estimation of its size. Other imaging methods (computed tomography, ultrasonography) have an advantage in detection of liver metastases, while immunoscintigraphy is more specific for the assessment of malignant abdominal tumors and extrahepatic metastases.
Conclusions: The first results point out that Oncoscint CR-103 can be useful in diagnosis of recurrences and metastases of colorectal carcinoma, viability assessment after radiotherapy and in the choice of the adequate surgical treatment in dependence of the spread of the disease.
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