PCR for vacA and cagA genotypes of Helicobacter pylori using DNA isolated from infected gastric biopsy specimens was approximately equal to genotyping using bacterial DNA from cultures. Inconsistent results were associated with low H. pylori density in biopsies. A higher proportion of mixed infection was found when biopsies were used.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC165374PMC
http://dx.doi.org/10.1128/JCM.41.7.3336-3338.2003DOI Listing

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