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http://dx.doi.org/10.1136/bmj.327.7405.s3 | DOI Listing |
Med Sci Sports Exerc
January 2025
Department of Developmental and Behavioral Health, Children's Mercy Kansas City, Kansas City, MO.
Kinesiophobia (KP) is the fear of movement or physical activity (PA) that is related to a medical condition. In adolescents, KP is associated with depression, anxiety, and impaired quality of life (QoL). Adolescents with heart disease (HD) often avoid PA.
View Article and Find Full Text PDFBMC Nurs
January 2025
Department of Nursing Sciences, College of Applied Medical Sciences, Shaqra University, Shaqra, Saudi Arabia.
Background: College-aged students are at risk for experiencing negative events that may influence their future health and life. Those negative events or stressors may vary in type and severity. Stress and bullying are prevalent among nursing students that may affect their academic motivation.
View Article and Find Full Text PDFNeurosurgery
January 2025
Department of Neurological Surgery, University of California San Diego, San Diego, California, USA.
Dr. Joan Venes (1935-2010) is a well-respected pioneer of pediatric neurosurgery. She was the third board-certified female neurosurgeon in the United States and was the first female neurosurgery resident to be accepted by her residency program at Yale University.
View Article and Find Full Text PDFMol Psychiatry
January 2025
Department of Psychiatry, New York University Grossman School of Medicine, New York, NY, USA.
A major challenge in the development of more effective therapeutic strategies for Alzheimer's disease (AD) is the identification of molecular mechanisms linked to specific pathophysiological features of the disease. Importantly AD has a two-fold higher incidence in women than men and a protracted prodromal phase characterized by amnestic mild-cognitive impairment (aMCI) suggesting that biological processes occurring early can initiate vulnerability to AD. Here, we used a sample of 125 subjects from two independent study cohorts to determine the levels in plasma (the most accessible specimen) of two essential mitochondrial markers acetyl-L-carnitine (LAC) and its derivative free-carnitine motivated by a mechanistic model in rodents in which targeting mitochondrial metabolism of LAC leads to the amelioration of cognitive function and boosts epigenetic mechanisms of gene expression.
View Article and Find Full Text PDFVaccines (Basel)
December 2024
School of Public Health, University of Texas Health Science Center at Houston, 7000 Fannin St., Houston, TX 77030, USA.
: Pediatrician recommendations are highly influential in parents' decisions to vaccinate their children against HPV. Unqualified, presumptive, and bundled recommendations (UPBRs) are associated with increased HPV vaccine uptake and are considered best practice. This study analyzes pediatricians' self-reported data to assess changes in UPBR use and the psychosocial determinants of UPBR use as a result of the implementation of a multi-level intervention, the Adolescent Vaccination Program (AVP).
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