Specific complex antigen, based on human serum albumin and epichlorhydrine was proved to be useful in the diagnosis of individual hypersensitivity to the epoxide pitches and epichlorhydrine. Lymphocytes' blast transformation with 3H-timidine was proved to be the most sensitive reaction in the use of specific complex antigen during the diagnosis. The stated immune reaction can be used for the diagnosis of allergy before the clinical manifestations.

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