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Nicolau's syndrome: A rare but preventable iatrogenic disease.
Acta Dermatovenerol Croat
October 2017
Assist. Prof. Tasleem Arif, MD, Postgraduate Department of Dermatology, STDs and Leprosy, Jawaharlal Nehru Medical College (JNMC), Aligarh Muslim University, Aligarh, India;
Article Synopsis
- Nicolau's syndrome is a rare reaction that can happen after getting injections, causing pain and a specific skin pattern at the injection site.
- The text talks about two cases where this syndrome occurred after injections of triamcinolone and diclofenac sodium.
- In both cases, the patients experienced severe pain and noticeable discoloration, leading to other complications like ulcers in one case.
Drug-related hospital admissions--an overview of frequency and clinical presentation.
Acta Pol Pharm
June 2007
Department of Dermatology, University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznań, Poland.
Adverse drug reactions (ADR) are the cause of hospital admissions for millions of patients every year and are believed to be a major problem in terms of morbidity and hospital expenses. ADR are characterized by exceptional variety, both considering pathomechanism and clinical symptoms. During the time period between 2000-2004 at the Department of Dermatology a project was undertaken to monitor patients who were hospitalized as a result of ADR.
View Article and Find Full Text PDF[Adverse drug reactions in patients attending in emergency service].
Rev Salud Publica (Bogota)
February 2007
Universidad Tecnológica de Pereira, Departamento de Farmacoepidemiología Audifarma S.A.
Objective: Describing adverse drug reactions (ADR) and analyzing the factors associated with their appearance in patients attending two hospitals' emergency services.
Methods: Descriptive, medicine-surveillance study of people consulting the emergency service at the Rosales hospital and the basic total health attention unit in Pereira, Colombia, between July and September 2005 for any symptom related to taking medicine. Naranjo's Adverse Drug Reaction probability scale was used.
We describe an unusual case of morbilliform skin eruption caused by diethylstilbestrol in a patient with stage D prostatic cancer. A widespread erythematous maculopapular rash and urticaria appeared with repeated challenges of diethylstilbestrol and resolved with drug withdrawal. In addition, the literature on various types of dermatitis medicamentosa in male patients with prostatic cancer treated with diethylstilbestrol is reviewed.
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