The use of Raman spectroscopy to identify and grade prostatic adenocarcinoma in vitro.

Br J Cancer

Cranfield Post-Graduate Medical School, Pullman Court, Gloucestershire Royal Hospital, Great Western Road, Gloucester, GL1 3NN, UK.

Published: July 2003

Raman spectroscopy is an optical technique, which provides a measure of the molecular composition of tissue. Raman spectra were recorded in vitro from both benign and malignant prostate biopsies, and used to construct a diagnostic algorithm. The algorithm was able to correctly identify each pathological group studied with an overall accuracy of 89%. The technique shows promise as a method for objectively grading prostate cancer.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394218PMC
http://dx.doi.org/10.1038/sj.bjc.6601059DOI Listing

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