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Our study was designed to update the HIV Knowledge Questionnaire by incorporating pre-exposure prophylaxis (PrEP) knowledge questions, as previous HIV knowledge tools lack this focus. Four rounds of Delphi surveys were conducted with 47 expert participants, each with extensive HIV-related expertise (mean experience: 18.94 years).

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The US faces substantial demographic and geographic disparities in both HIV burden and access to pre-exposure prophylaxis (PrEP), an effective strategy to prevent HIV acquisition. Long-acting cabotegravir (CAB) is a novel, injectable PrEP option which demonstrated superior reduction in risk of HIV acquisition compared to daily-oral PrEP in the HPTN083 trial. We modelled the impact of increased PrEP initiations and the introduction of long-acting CAB on HIV incidence among men who have sex with men (MSM) in Atlanta, Georgia, a population with a high burden of HIV.

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Background: Adolescents who have the human immunodeficiency virus face difficulties in their lives not just from the physical consequences of the illness but also from social stigma and discrimination. The quantitative side of this issue was the focus of earlier Ethiopian research. However, there hasn't been any prior research done extensively in Ethiopia on the real-life experiences of teenagers infected with HIV.

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Public Health.

Alzheimers Dement

December 2024

Boramae Medical Center, Seoul, Dongjak, Korea, Republic of (South).

Background: Cognitive decline often follows human immunodeficiency virus (HIV) infection, yet the specific risk factors for developing Alzheimer's disease and related dementia (ADRD) in HIV patients remain elusive.

Method: To investigate the association between acquired immune deficiency syndrome (AIDS) status at the time of HIV diagnosis and the risk of ADRD, we conducted a retrospective cohort study using data from a nationwide claim database spanning 2008 to 2021. During the study period, 13,289 patients were newly diagnosed with HIV infection and were prescribed antiretroviral therapy (ART).

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Public Health.

Alzheimers Dement

December 2024

King's College London, Strand, London, United Kingdom.

Background: The prevalence of dementia in low- and middle-income countries is increasing, yet epidemiological data from African populations remains scarce. Crucial risk factors differ in Africa from more intensively studied global areas, including a high burden of cerebrovascular disease (evidenced by high stroke incidence) and HIV, but lower rates of other risk factors such as physical inactivity. In the pre-antiretroviral therapy era, dementia was a common consequence of HIV infection.

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