This article provides an overview of and rationale for wound bed preparation. It seeks to increase nurses' knowledge and understanding of the roles of the main cells and growth factors, involved in the wound healing process, and also to highlight how theory relates to practice.
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Platelet extracellular vesicles-loaded hydrogel bandages for personalized wound care.
Trends Biotechnol
January 2025
Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City 235603, Taiwan; International PhD Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City 235603, Taiwan; International PhD Program in Cell Therapy and Regenerative Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. Electronic address:
Autologous or allogeneic platelet-derived extracellular vesicles (pEVs) show potential in enhancing tissue recovery and healing chronic wounds. pEVs promote neovascularization and cell migration while reducing inflammation, oxidative stress, and scarring. However, their efficacy in clinical settings is challenged by their susceptibility to washout by wound exudate.
View Article and Find Full Text PDFNegative pressure wound therapy on a musculocutaneous free flap in no skin edge wound bed: A case report.
Int J Surg Case Rep
January 2025
Department of Plastic and Breast Surgery, Aarhus University Hospital, Denmark.
Introduction: Necrotising soft tissue infection (NSTI) is an exceptionally dangerous infectious disease targeting soft tissues with high mortality as well as morbidity. The aim of reconstructive surgery after initial debridement is to maintain function as well as to achieve a satisfactory cosmetic result.
Presentation Of Case: A 50-year-old male presented with necrotising soft tissue infection on the thorax and left upper arm following mastectomy for breast cancer.
IMPROVEMENT OF LOWER LIMB AMPUTATION PROCEDURE IN PATIENTS WITH CRITICAL LOWER LIMB ISCHAEMIA.
Georgian Med News
November 2024
5Department of Hospital Surgery, Anesthesiology and Reanimatology, Non-Commercial Joint-Stock Company "Semey Medical University" (NCJSC «SMU»), Republic of Kazakhstan.
The relevance of the presented topic lies in the rapid growth of complications from diseases that subsequently lead to limb amputation, as well as the problem of untimely detection of ischemic tissues. The aim of the study is to determine and explain the main progressive methods of surgical treatment of obstructive diseases of vessels of different calibers that lead to circulatory disorders and tissue necrosis. The following research methods were used in the work: statistical method, bibliographic, and bibliosemantic.
View Article and Find Full Text PDFThe use of rehabilitation beds following hip fracture leads to an increased length of stay.
Acta Orthop Belg
September 2024
The aim of this paper is to identify if there is a difference in length of stay following hip fractures when using rehabilitation beds. Prospective data was collected on all hip fracture admissions in patients over 50 years from May 2016 to February 2018 from ISD NHS Scotland to identify length of stay. It was found that patients discharged home via rehabilitation wards were less likely to have returned to their own home by 30 days post admission and were also significantly more likely to stay in hospital for 40 days or more when compared to patients discharged directly home.
View Article and Find Full Text PDFCase report: Surgical closure of a facial defect in an African wild dog () utilizing a transpositional skin flap.
Front Vet Sci
January 2025
College of Veterinary Medicine, Michigan State University, East Lansing, MI, United States.
Veterinary intervention in zoological species can be complicated by species-specific social dynamics. African wild dogs are a pack species and removal or separation of an individual may disrupt established pack hierarchy resulting in conspecific aggression. Therefore, medical interventions that optimize a quick return to health are ideal to minimize the duration of absence from the pack.
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